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Xanthogranuloma of the sellar region.
Acta Neurochir (Wien). 2006 Apr; 148(4):473-7.AN

Abstract

The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.

Authors+Show Affiliations

Jung CS
Department of Neurosurgery, Johann-Wolfgang Goethe University Frankfurt, Frankfurt, Germany. c.s.jung@em.uni-frankfurt.de
Schänzer A
No affiliation info available
Hattingen E
No affiliation info available
Plate KH
No affiliation info available
Seifert V
No affiliation info available

MeSH

Child, PreschoolCholesterolCraniopharyngiomaDiagnosis, DifferentialFemaleGiant Cells, Foreign-BodyHemosiderinHumansHypopituitarismLymphocytesMacrophagesMaleMiddle AgedNeurosurgical ProceduresPituitary GlandPostoperative ComplicationsSella TurcicaSkull Base NeoplasmsTreatment OutcomeXanthogranuloma, Juvenile

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16341628

Citation

Jung, C S., et al. "Xanthogranuloma of the Sellar Region." Acta Neurochirurgica, vol. 148, no. 4, 2006, pp. 473-7.
Jung CS, Schänzer A, Hattingen E, et al. Xanthogranuloma of the sellar region. Acta Neurochir (Wien). 2006;148(4):473-7.
Jung, C. S., Schänzer, A., Hattingen, E., Plate, K. H., & Seifert, V. (2006). Xanthogranuloma of the sellar region. Acta Neurochirurgica, 148(4), 473-7.
Jung CS, et al. Xanthogranuloma of the Sellar Region. Acta Neurochir (Wien). 2006;148(4):473-7. PubMed PMID: 16341628.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Xanthogranuloma of the sellar region. AU - Jung,C S, AU - Schänzer,A, AU - Hattingen,E, AU - Plate,K H, AU - Seifert,V, Y1 - 2005/12/12/ PY - 2005/06/09/received PY - 2005/10/26/accepted PY - 2005/12/13/pubmed PY - 2006/9/1/medline PY - 2005/12/13/entrez SP - 473 EP - 7 JF - Acta neurochirurgica JO - Acta Neurochir (Wien) VL - 148 IS - 4 N2 - The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis. SN - 0001-6268 UR - https://www.unboundmedicine.com/medline/citation/16341628/Xanthogranuloma_of_the_sellar_region_ DB - PRIME DP - Unbound Medicine ER -