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Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli.
Arch Pharm Res. 2005 Nov; 28(11):1239-43.AP

Abstract

A new norditerpenoid and a known alkaloid were isolated from the alkaloidal fraction of the processed tubers of Aconitum carmichaeli. The structure of the new norditerpenoid alkaloid was elucidated as lipoforesaconitine (1) on the basis of spectroscopic analysis. The known norditerpenoid alkaloid was characterized as lipoyunanaconitine (2). In addition, a new flavonoid, 6"-O-acetylliquiritin (7), along with a known ceramide, (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxylignoceroylamino]-8(E)-octadecene-1,3,4-triol (3), as well as a known steroid saponin, gracillin (8), and three known flavonoids, liquiritigenin (4), isoliquiritigenin (5), and liquiritin (6), were also isolated and characterized. All known compounds were isolated from this plant for the first time. The structures of the isolates were established by spectroscopic and chemical methods.

Authors+Show Affiliations

Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16350849

Citation

Shim, Sang Hee, et al. "Norditerpenoid Alkaloids and Other Components From the Processed Tubers of Aconitum Carmichaeli." Archives of Pharmacal Research, vol. 28, no. 11, 2005, pp. 1239-43.
Shim SH, Lee SY, Kim JS, et al. Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli. Arch Pharm Res. 2005;28(11):1239-43.
Shim, S. H., Lee, S. Y., Kim, J. S., Son, K. H., & Kang, S. S. (2005). Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli. Archives of Pharmacal Research, 28(11), 1239-43.
Shim SH, et al. Norditerpenoid Alkaloids and Other Components From the Processed Tubers of Aconitum Carmichaeli. Arch Pharm Res. 2005;28(11):1239-43. PubMed PMID: 16350849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli. AU - Shim,Sang Hee, AU - Lee,So Young, AU - Kim,Ju Sun, AU - Son,Kun Ho, AU - Kang,Sam Sik, PY - 2005/12/15/pubmed PY - 2006/2/4/medline PY - 2005/12/15/entrez SP - 1239 EP - 43 JF - Archives of pharmacal research JO - Arch Pharm Res VL - 28 IS - 11 N2 - A new norditerpenoid and a known alkaloid were isolated from the alkaloidal fraction of the processed tubers of Aconitum carmichaeli. The structure of the new norditerpenoid alkaloid was elucidated as lipoforesaconitine (1) on the basis of spectroscopic analysis. The known norditerpenoid alkaloid was characterized as lipoyunanaconitine (2). In addition, a new flavonoid, 6"-O-acetylliquiritin (7), along with a known ceramide, (2S,3S,4R,8E)-2-[(2'R)-2'-hydroxylignoceroylamino]-8(E)-octadecene-1,3,4-triol (3), as well as a known steroid saponin, gracillin (8), and three known flavonoids, liquiritigenin (4), isoliquiritigenin (5), and liquiritin (6), were also isolated and characterized. All known compounds were isolated from this plant for the first time. The structures of the isolates were established by spectroscopic and chemical methods. SN - 0253-6269 UR - https://www.unboundmedicine.com/medline/citation/16350849/Norditerpenoid_alkaloids_and_other_components_from_the_processed_tubers_of_Aconitum_carmichaeli_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=16350849.ui DB - PRIME DP - Unbound Medicine ER -