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Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms.
J Korean Med Sci. 2005 Dec; 20(6):971-6.JK

Abstract

Behcet's disease (BD) is a multisystemic chronic inflammatory disease. It is characterized by recurrent oral and genital ulcers, uveitis, skin lesions and other manifestations, including neurologic, vascular, joint, and gastrointestinal ulcers of variable severity. Recurrent aphthous ulcer (RAU) represents a very common, but poorly understood, mucosal disorder. If a patient of RAU without any other typical symptoms of BD has gastrointestinal symptoms, it is difficult to distinguish this RAU from true BD with gastrointestinal involvement. Because pathognomonic clinical features and tools are absent, the differential diagnosis of these two diseases relies on the characteristic clinical features and the judgement of an experienced physician. Sixty-five out of a total 960 RAU patients and forty-four of 556 BD patients with gastrointestinal symptoms between January 1996 and December 2003 participated in this study. All were evaluated with esophagogastroduodenoscopy and colonoscopy. Clinical, endoscopic and histopathologic findings were analyzed and ELISA tests were conducted to detect serum levels of ASCA and pANCA. No significant difference was found between the two groups. Differential diagnosis between RAU with gastrointestinal symptoms and BD with gastrointestinal involvement requires further prospective, large-scale study.

Authors+Show Affiliations

Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16361807

Citation

Rhee, Seung-Ho, et al. "Comparison of Behcet's Disease and Recurrent Aphthous Ulcer According to Characteristics of Gastrointestinal Symptoms." Journal of Korean Medical Science, vol. 20, no. 6, 2005, pp. 971-6.
Rhee SH, Kim YB, Lee ES. Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms. J Korean Med Sci. 2005;20(6):971-6.
Rhee, S. H., Kim, Y. B., & Lee, E. S. (2005). Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms. Journal of Korean Medical Science, 20(6), 971-6.
Rhee SH, Kim YB, Lee ES. Comparison of Behcet's Disease and Recurrent Aphthous Ulcer According to Characteristics of Gastrointestinal Symptoms. J Korean Med Sci. 2005;20(6):971-6. PubMed PMID: 16361807.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms. AU - Rhee,Seung-Ho, AU - Kim,Young-Bae, AU - Lee,Eun-So, PY - 2005/12/20/pubmed PY - 2006/3/21/medline PY - 2005/12/20/entrez SP - 971 EP - 6 JF - Journal of Korean medical science JO - J. Korean Med. Sci. VL - 20 IS - 6 N2 - Behcet's disease (BD) is a multisystemic chronic inflammatory disease. It is characterized by recurrent oral and genital ulcers, uveitis, skin lesions and other manifestations, including neurologic, vascular, joint, and gastrointestinal ulcers of variable severity. Recurrent aphthous ulcer (RAU) represents a very common, but poorly understood, mucosal disorder. If a patient of RAU without any other typical symptoms of BD has gastrointestinal symptoms, it is difficult to distinguish this RAU from true BD with gastrointestinal involvement. Because pathognomonic clinical features and tools are absent, the differential diagnosis of these two diseases relies on the characteristic clinical features and the judgement of an experienced physician. Sixty-five out of a total 960 RAU patients and forty-four of 556 BD patients with gastrointestinal symptoms between January 1996 and December 2003 participated in this study. All were evaluated with esophagogastroduodenoscopy and colonoscopy. Clinical, endoscopic and histopathologic findings were analyzed and ELISA tests were conducted to detect serum levels of ASCA and pANCA. No significant difference was found between the two groups. Differential diagnosis between RAU with gastrointestinal symptoms and BD with gastrointestinal involvement requires further prospective, large-scale study. SN - 1011-8934 UR - https://www.unboundmedicine.com/medline/citation/16361807/Comparison_of_Behcet's_disease_and_recurrent_aphthous_ulcer_according_to_characteristics_of_gastrointestinal_symptoms_ L2 - https://jkms.org/DOIx.php?id=10.3346/jkms.2005.20.6.971 DB - PRIME DP - Unbound Medicine ER -