Tags

Type your tag names separated by a space and hit enter

Self-reported mental health difficulties and subsequent risk for schizophrenia in females: a 5-year follow-up cohort study.
Schizophr Res. 2006 Feb 28; 82(2-3):233-9.SR

Abstract

BACKGROUND

Patients with schizophrenia often report a history of premorbid mild to severe psychological distress. We investigated the association between self-reported mental health difficulties and later psychiatric hospitalization for schizophrenia.

METHODS

13,357 females aged 17, mandatory assessed by the Israeli Draft Board were followed up over 5 years for psychiatric hospitalization by means of the Israeli National Psychiatric Hospitalization Case Registry. Seventeen females, judged healthy at Draft Board assessment, were hospitalized for schizophrenia or schizoaffective disorder over the follow-up period.

RESULTS

There was a significant monotonic association between increasing self-reported mental health difficulties (psychological distress and increasing need for psychological counseling) and prevalence of schizophrenia [odds ratios over four levels: 1.56; 95% CI:1.04 to 2.34; chi2 (1) = 4.62, p = 0.03], after controlling for low IQ, immigration, SES, and presence of psychiatric disorders at age 17. Increasing severity of self-reported mental health difficulties was related to earlier age of first hospitalization [r = -0.48, p = 0.05].

CONCLUSIONS

Increased undifferentiated self-reported mental health difficulties are associated with increased risk of later hospitalization for schizophrenia prior to age 23 in females. This may reflect the prodromal phase of the illness.

Authors+Show Affiliations

Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1230, New York, NY 10029, USA. avi.reichenberg@mssm.eduNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16364598

Citation

Reichenberg, Abraham, and Judy Goldenberg. "Self-reported Mental Health Difficulties and Subsequent Risk for Schizophrenia in Females: a 5-year Follow-up Cohort Study." Schizophrenia Research, vol. 82, no. 2-3, 2006, pp. 233-9.
Reichenberg A, Goldenberg J. Self-reported mental health difficulties and subsequent risk for schizophrenia in females: a 5-year follow-up cohort study. Schizophr Res. 2006;82(2-3):233-9.
Reichenberg, A., & Goldenberg, J. (2006). Self-reported mental health difficulties and subsequent risk for schizophrenia in females: a 5-year follow-up cohort study. Schizophrenia Research, 82(2-3), 233-9.
Reichenberg A, Goldenberg J. Self-reported Mental Health Difficulties and Subsequent Risk for Schizophrenia in Females: a 5-year Follow-up Cohort Study. Schizophr Res. 2006 Feb 28;82(2-3):233-9. PubMed PMID: 16364598.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Self-reported mental health difficulties and subsequent risk for schizophrenia in females: a 5-year follow-up cohort study. AU - Reichenberg,Abraham, AU - Goldenberg,Judy, Y1 - 2005/12/20/ PY - 2005/06/14/received PY - 2005/11/03/revised PY - 2005/11/10/accepted PY - 2005/12/21/pubmed PY - 2006/9/9/medline PY - 2005/12/21/entrez SP - 233 EP - 9 JF - Schizophrenia research JO - Schizophr Res VL - 82 IS - 2-3 N2 - BACKGROUND: Patients with schizophrenia often report a history of premorbid mild to severe psychological distress. We investigated the association between self-reported mental health difficulties and later psychiatric hospitalization for schizophrenia. METHODS: 13,357 females aged 17, mandatory assessed by the Israeli Draft Board were followed up over 5 years for psychiatric hospitalization by means of the Israeli National Psychiatric Hospitalization Case Registry. Seventeen females, judged healthy at Draft Board assessment, were hospitalized for schizophrenia or schizoaffective disorder over the follow-up period. RESULTS: There was a significant monotonic association between increasing self-reported mental health difficulties (psychological distress and increasing need for psychological counseling) and prevalence of schizophrenia [odds ratios over four levels: 1.56; 95% CI:1.04 to 2.34; chi2 (1) = 4.62, p = 0.03], after controlling for low IQ, immigration, SES, and presence of psychiatric disorders at age 17. Increasing severity of self-reported mental health difficulties was related to earlier age of first hospitalization [r = -0.48, p = 0.05]. CONCLUSIONS: Increased undifferentiated self-reported mental health difficulties are associated with increased risk of later hospitalization for schizophrenia prior to age 23 in females. This may reflect the prodromal phase of the illness. SN - 0920-9964 UR - https://www.unboundmedicine.com/medline/citation/16364598/Self_reported_mental_health_difficulties_and_subsequent_risk_for_schizophrenia_in_females:_a_5_year_follow_up_cohort_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0920-9964(05)00497-4 DB - PRIME DP - Unbound Medicine ER -