Tags

Type your tag names separated by a space and hit enter

A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS).
Physiol Meas. 2006 Jan; 27(1):13-22.PM

Abstract

Thirty volunteers (19 males, 11 females) were recruited for a 6-month study of the volatile compounds in their exhaled breath using the selected ion flow tube mass spectrometry (SIFT-MS) analytical technique. Volunteers provided weekly breath samples between 8:45 am and 1 pm (before lunch), and the concentrations of several trace compounds were obtained. In this paper, we focus on the isoprene in alveolar breath, which was monitored by SIFT-MS using NO(+) precursor ions. The mean isoprene level for all samples was 118 parts per billion (ppb) with a standard deviation of 68 ppb and the range of values for breath samples given is 0-474 ppb. Variability in isoprene levels was similar in most volunteers. Isoprene levels increased immediately after moderate exercise, but returned to normal within 2-3 min for those few volunteers that were investigated. Cholesterol levels analysed for only three of the subjects were not obviously correlated with isoprene concentration in breath. Differences in isoprene levels were not directly correlated to gender, age or body mass index.

Authors+Show Affiliations

Silsoe Research Institute, Wrest Park, Silsoe, Bedford MK45 4HS, UK. c.turner@cranfield.ac.ukNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16365507

Citation

Turner, Claire, et al. "A Longitudinal Study of Breath Isoprene in Healthy Volunteers Using Selected Ion Flow Tube Mass Spectrometry (SIFT-MS)." Physiological Measurement, vol. 27, no. 1, 2006, pp. 13-22.
Turner C, Spanel P, Smith D. A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS). Physiol Meas. 2006;27(1):13-22.
Turner, C., Spanel, P., & Smith, D. (2006). A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS). Physiological Measurement, 27(1), 13-22.
Turner C, Spanel P, Smith D. A Longitudinal Study of Breath Isoprene in Healthy Volunteers Using Selected Ion Flow Tube Mass Spectrometry (SIFT-MS). Physiol Meas. 2006;27(1):13-22. PubMed PMID: 16365507.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A longitudinal study of breath isoprene in healthy volunteers using selected ion flow tube mass spectrometry (SIFT-MS). AU - Turner,Claire, AU - Spanel,Patrik, AU - Smith,David, Y1 - 2005/11/29/ PY - 2005/12/21/pubmed PY - 2006/3/3/medline PY - 2005/12/21/entrez SP - 13 EP - 22 JF - Physiological measurement JO - Physiol Meas VL - 27 IS - 1 N2 - Thirty volunteers (19 males, 11 females) were recruited for a 6-month study of the volatile compounds in their exhaled breath using the selected ion flow tube mass spectrometry (SIFT-MS) analytical technique. Volunteers provided weekly breath samples between 8:45 am and 1 pm (before lunch), and the concentrations of several trace compounds were obtained. In this paper, we focus on the isoprene in alveolar breath, which was monitored by SIFT-MS using NO(+) precursor ions. The mean isoprene level for all samples was 118 parts per billion (ppb) with a standard deviation of 68 ppb and the range of values for breath samples given is 0-474 ppb. Variability in isoprene levels was similar in most volunteers. Isoprene levels increased immediately after moderate exercise, but returned to normal within 2-3 min for those few volunteers that were investigated. Cholesterol levels analysed for only three of the subjects were not obviously correlated with isoprene concentration in breath. Differences in isoprene levels were not directly correlated to gender, age or body mass index. SN - 0967-3334 UR - https://www.unboundmedicine.com/medline/citation/16365507/A_longitudinal_study_of_breath_isoprene_in_healthy_volunteers_using_selected_ion_flow_tube_mass_spectrometry__SIFT_MS__ L2 - https://doi.org/10.1088/0967-3334/27/1/002 DB - PRIME DP - Unbound Medicine ER -