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Diagnosis, treatment, and management of irritable bowel syndrome with constipation and chronic constipation.
MedGenMed 2005; 7(3):71M

Abstract

Irritable bowel syndrome with constipation (IBS-C) and chronic constipation are 2 common gastrointestinal motility disorders that place a substantial burden on patients and society. Symptoms of both disorders are chronic, sometimes severe, and often respond poorly to treatment with traditional approaches, resulting in reduced quality of life, polypharmacy, and frequent healthcare utilization. Because structural, physical, or biochemical markers cannot be used to identify either disorder, diagnosis is symptom-based. In the absence of alarm features suggestive of organic disease or secondary causes of symptoms, these disorders can be positively and confidently diagnosed. In general, traditional agents used to treat patients with constipation target only a single symptom, and do not provide adequate relief of symptoms in the majority of IBS-C patients. Although patients with mild constipation symptoms may respond to treatment with fiber and laxatives, others with moderate-to-severe symptoms may require additional therapies and/or referral to a specialist for further evaluation. The advent of novel serotonergic agents has rejuvenated the therapeutic approach to patients with IBS-C and chronic constipation.

Authors+Show Affiliations

The Weill Medical College of Cornell University, New York, NY, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16369297

Citation

Frissora, Christine L.. "Diagnosis, Treatment, and Management of Irritable Bowel Syndrome With Constipation and Chronic Constipation." MedGenMed : Medscape General Medicine, vol. 7, no. 3, 2005, p. 71.
Frissora CL. Diagnosis, treatment, and management of irritable bowel syndrome with constipation and chronic constipation. MedGenMed. 2005;7(3):71.
Frissora, C. L. (2005). Diagnosis, treatment, and management of irritable bowel syndrome with constipation and chronic constipation. MedGenMed : Medscape General Medicine, 7(3), p. 71.
Frissora CL. Diagnosis, Treatment, and Management of Irritable Bowel Syndrome With Constipation and Chronic Constipation. MedGenMed. 2005 Aug 10;7(3):71. PubMed PMID: 16369297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis, treatment, and management of irritable bowel syndrome with constipation and chronic constipation. A1 - Frissora,Christine L, Y1 - 2005/08/10/ PY - 2005/12/22/pubmed PY - 2006/7/14/medline PY - 2005/12/22/entrez SP - 71 EP - 71 JF - MedGenMed : Medscape general medicine JO - MedGenMed VL - 7 IS - 3 N2 - Irritable bowel syndrome with constipation (IBS-C) and chronic constipation are 2 common gastrointestinal motility disorders that place a substantial burden on patients and society. Symptoms of both disorders are chronic, sometimes severe, and often respond poorly to treatment with traditional approaches, resulting in reduced quality of life, polypharmacy, and frequent healthcare utilization. Because structural, physical, or biochemical markers cannot be used to identify either disorder, diagnosis is symptom-based. In the absence of alarm features suggestive of organic disease or secondary causes of symptoms, these disorders can be positively and confidently diagnosed. In general, traditional agents used to treat patients with constipation target only a single symptom, and do not provide adequate relief of symptoms in the majority of IBS-C patients. Although patients with mild constipation symptoms may respond to treatment with fiber and laxatives, others with moderate-to-severe symptoms may require additional therapies and/or referral to a specialist for further evaluation. The advent of novel serotonergic agents has rejuvenated the therapeutic approach to patients with IBS-C and chronic constipation. SN - 1531-0132 UR - https://www.unboundmedicine.com/medline/citation/16369297/Diagnosis_treatment_and_management_of_irritable_bowel_syndrome_with_constipation_and_chronic_constipation_ L2 - http://www.medscape.com/viewarticle/509930 DB - PRIME DP - Unbound Medicine ER -