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Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1.
Phytother Res. 2005 Dec; 19(12):1069-70.PR

Abstract

Andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide, ent-labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV-1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations.

Authors+Show Affiliations

Wiart C
Department of Pharmacy, Faculty of Medicine, University of Malaya, Malaysia. christophe_wiart@yahoo.com
Kumar K
No affiliation info available
Yusof MY
No affiliation info available
Hamimah H
No affiliation info available
Fauzi ZM
No affiliation info available
Sulaiman M
No affiliation info available

MeSH

AndrographisAnimalsAntiviral AgentsChlorocebus aethiopsDiterpenesGlucosidesHerpesvirus 1, HumanPlant ExtractsPlant LeavesTetrahydronaphthalenesVero Cells

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16372376

Citation

Wiart, C, et al. "Antiviral Properties of Ent-labdene Diterpenes of Andrographis Paniculata Nees, Inhibitors of Herpes Simplex Virus Type 1." Phytotherapy Research : PTR, vol. 19, no. 12, 2005, pp. 1069-70.
Wiart C, Kumar K, Yusof MY, et al. Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1. Phytother Res. 2005;19(12):1069-70.
Wiart, C., Kumar, K., Yusof, M. Y., Hamimah, H., Fauzi, Z. M., & Sulaiman, M. (2005). Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1. Phytotherapy Research : PTR, 19(12), 1069-70.
Wiart C, et al. Antiviral Properties of Ent-labdene Diterpenes of Andrographis Paniculata Nees, Inhibitors of Herpes Simplex Virus Type 1. Phytother Res. 2005;19(12):1069-70. PubMed PMID: 16372376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1. AU - Wiart,C, AU - Kumar,K, AU - Yusof,M Y, AU - Hamimah,H, AU - Fauzi,Z M, AU - Sulaiman,M, PY - 2005/12/24/pubmed PY - 2006/3/18/medline PY - 2005/12/24/entrez SP - 1069 EP - 70 JF - Phytotherapy research : PTR JO - Phytother Res VL - 19 IS - 12 N2 - Andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide, ent-labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV-1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations. SN - 0951-418X UR - https://www.unboundmedicine.com/medline/citation/16372376/Antiviral_properties_of_ent_labdene_diterpenes_of_Andrographis_paniculata_nees_inhibitors_of_herpes_simplex_virus_type_1_ DB - PRIME DP - Unbound Medicine ER -