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Anti-inflammatory activity of Coldenia procumbens Linn.
Pak J Pharm Sci. 2005 Jul; 18(3):17-20.PJ

Abstract

Anti-inflammatory activity of the ethanolic extract of the aerial parts of Coldenia procumbens Linn. was studied in Wister rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (150 mg/kg, p.o.) produced the inhibition of carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction on the pleural exudates as well as reduction on the granuloma weight in the cotton pellet granuloma method. The results indicated that the ethanolic extract produced significant (P<0.001) anti-inflammatory activity when compared with the standard and untreated control.

Authors+Show Affiliations

Arul B
Department of Pharmaceutics, Vinayaka Mission's College of Pharmacy, Yercaud Main Road, Salem-636 008, Tamilnadu, India. arul1971@yahoo.com
Kothai R
No affiliation info available
Sureshkumar K
No affiliation info available
Christina AJ
No affiliation info available

MeSH

AnimalsAnti-Inflammatory AgentsBoraginaceaeEdemaFemaleGranulomaLeukocytesMalePlant ExtractsRatsRats, Wistar

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16380339

Citation

Arul, B, et al. "Anti-inflammatory Activity of Coldenia Procumbens Linn." Pakistan Journal of Pharmaceutical Sciences, vol. 18, no. 3, 2005, pp. 17-20.
Arul B, Kothai R, Sureshkumar K, et al. Anti-inflammatory activity of Coldenia procumbens Linn. Pak J Pharm Sci. 2005;18(3):17-20.
Arul, B., Kothai, R., Sureshkumar, K., & Christina, A. J. (2005). Anti-inflammatory activity of Coldenia procumbens Linn. Pakistan Journal of Pharmaceutical Sciences, 18(3), 17-20.
Arul B, et al. Anti-inflammatory Activity of Coldenia Procumbens Linn. Pak J Pharm Sci. 2005;18(3):17-20. PubMed PMID: 16380339.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory activity of Coldenia procumbens Linn. AU - Arul,B, AU - Kothai,R, AU - Sureshkumar,K, AU - Christina,A J M, PY - 2005/12/29/pubmed PY - 2006/1/19/medline PY - 2005/12/29/entrez SP - 17 EP - 20 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 18 IS - 3 N2 - Anti-inflammatory activity of the ethanolic extract of the aerial parts of Coldenia procumbens Linn. was studied in Wister rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (150 mg/kg, p.o.) produced the inhibition of carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction on the pleural exudates as well as reduction on the granuloma weight in the cotton pellet granuloma method. The results indicated that the ethanolic extract produced significant (P<0.001) anti-inflammatory activity when compared with the standard and untreated control. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/16380339/Anti_inflammatory_activity_of_Coldenia_procumbens_Linn_ DB - PRIME DP - Unbound Medicine ER -