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Dietary and cancer-related behaviors of vitamin/mineral dietary supplement users in a large cohort of French women.
Eur J Nutr 2006; 45(4):205-14EJ

Abstract

BACKGROUND

Several epidemiological studies suggested an association between vitamin/mineral dietary supplement use and cancer risk. However, characteristics of supplement users may themselves be related to cancer risk, and therefore could confound such etiological studies. Very little is known about the characteristics of French supplement users.

AIM OF THE STUDY

To identify cancer-related behaviors and dietary characteristics of vitamin/mineral supplement users in the E3N cohort of French women.

METHODS

Data on supplement use and cancer-related and socio-demographic characteristics were collected by self-administered questionnaires completed by 83,058 women, 67,229 of whom also completed a food frequency questionnaire. Supplement users were compared to non-users by unconditional logistic regression.

RESULTS

Vitamin/mineral supplement users were significantly older and leaner (odds ratio [OR] for BMI >or= 30 vs. <18.5 kg/m2 = 0.35, 95% confidence interval [CI] 0.31-0.39), were less often current smokers, had a higher level of education and had more leisure physical activity. They used more phytooestrogen supplements (OR=3.95, 95 % CI 3.69-4.23), had more often a family history of breast cancer and had more often undergone cancer-screening. Users tended to have a healthier diet: less alcohol, more vegetables, fruit, dairy products, fish and soups. They had higher dietary intakes for most micro-nutrients, fiber and omega3 fatty acids, lower fat intake and either similar or lower prevalence of inadequate dietary intake for all relevant nutrients except magnesium.

CONCLUSIONS

To avoid major confounding, the lifestyle characteristics of supplement users should be considered in studies investigating the association between supplement use and cancer risk.

Authors+Show Affiliations

AFSSA-French Food Safety Agency DERNS/OCA, Maisons-Alfort, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16382374

Citation

Touvier, Mathilde, et al. "Dietary and Cancer-related Behaviors of Vitamin/mineral Dietary Supplement Users in a Large Cohort of French Women." European Journal of Nutrition, vol. 45, no. 4, 2006, pp. 205-14.
Touvier M, Kesse E, Volatier JL, et al. Dietary and cancer-related behaviors of vitamin/mineral dietary supplement users in a large cohort of French women. Eur J Nutr. 2006;45(4):205-14.
Touvier, M., Kesse, E., Volatier, J. L., Clavel-Chapelon, F., & Boutron-Ruault, M. C. (2006). Dietary and cancer-related behaviors of vitamin/mineral dietary supplement users in a large cohort of French women. European Journal of Nutrition, 45(4), pp. 205-14.
Touvier M, et al. Dietary and Cancer-related Behaviors of Vitamin/mineral Dietary Supplement Users in a Large Cohort of French Women. Eur J Nutr. 2006;45(4):205-14. PubMed PMID: 16382374.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary and cancer-related behaviors of vitamin/mineral dietary supplement users in a large cohort of French women. AU - Touvier,Mathilde, AU - Kesse,Emmanuelle, AU - Volatier,Jean-Luc, AU - Clavel-Chapelon,Françoise, AU - Boutron-Ruault,Marie-Christine, Y1 - 2006/01/02/ PY - 2005/04/18/received PY - 2005/10/20/accepted PY - 2005/12/31/pubmed PY - 2007/5/15/medline PY - 2005/12/31/entrez SP - 205 EP - 14 JF - European journal of nutrition JO - Eur J Nutr VL - 45 IS - 4 N2 - BACKGROUND: Several epidemiological studies suggested an association between vitamin/mineral dietary supplement use and cancer risk. However, characteristics of supplement users may themselves be related to cancer risk, and therefore could confound such etiological studies. Very little is known about the characteristics of French supplement users. AIM OF THE STUDY: To identify cancer-related behaviors and dietary characteristics of vitamin/mineral supplement users in the E3N cohort of French women. METHODS: Data on supplement use and cancer-related and socio-demographic characteristics were collected by self-administered questionnaires completed by 83,058 women, 67,229 of whom also completed a food frequency questionnaire. Supplement users were compared to non-users by unconditional logistic regression. RESULTS: Vitamin/mineral supplement users were significantly older and leaner (odds ratio [OR] for BMI >or= 30 vs. <18.5 kg/m2 = 0.35, 95% confidence interval [CI] 0.31-0.39), were less often current smokers, had a higher level of education and had more leisure physical activity. They used more phytooestrogen supplements (OR=3.95, 95 % CI 3.69-4.23), had more often a family history of breast cancer and had more often undergone cancer-screening. Users tended to have a healthier diet: less alcohol, more vegetables, fruit, dairy products, fish and soups. They had higher dietary intakes for most micro-nutrients, fiber and omega3 fatty acids, lower fat intake and either similar or lower prevalence of inadequate dietary intake for all relevant nutrients except magnesium. CONCLUSIONS: To avoid major confounding, the lifestyle characteristics of supplement users should be considered in studies investigating the association between supplement use and cancer risk. SN - 1436-6207 UR - https://www.unboundmedicine.com/medline/citation/16382374/Dietary_and_cancer_related_behaviors_of_vitamin/mineral_dietary_supplement_users_in_a_large_cohort_of_French_women_ L2 - https://dx.doi.org/10.1007/s00394-006-0587-x DB - PRIME DP - Unbound Medicine ER -