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Surgical implications of colorectal cancer genetics.
Surg Oncol Clin N Am. 2006 Jan; 15(1):51-66, vi.SO

Abstract

The applications of genetics in colorectal cancer are not limited to identifying germ-line mutations in genetically predisposed individuals. Reports on the use of molecular genetic markers as prognostic factors and for assessing the response to therapy are common in the literature. As the primary caregiver in the majority of these cases, the surgeon needs a basic knowledge of colorectal genetics and their implications to the patient and the patient's family. This article discusses a practical approach for some of the issues likely to be encountered by the surgeon.

Links

Publisher Full Text
linkinghub.elsevier.com
journals.elsevierhealth.com

Authors+Show Affiliations

Rodriguez-Bigas MA
Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 444, PO Box 301402, Houston, TX 77230-1402, USA. mrodbig@mdanderson.org
Chang GJ
No affiliation info available
Skibber JM
No affiliation info available

MeSH

Adenomatous Polyposis ColiColorectal NeoplasmsColorectal Neoplasms, Hereditary NonpolyposisGenetic MarkersGenetic Predisposition to DiseaseHumansNeoplastic Syndromes, HereditaryPeutz-Jeghers Syndrome

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16389150

Citation

Rodriguez-Bigas, Miguel A., et al. "Surgical Implications of Colorectal Cancer Genetics." Surgical Oncology Clinics of North America, vol. 15, no. 1, 2006, pp. 51-66, vi.
Rodriguez-Bigas MA, Chang GJ, Skibber JM. Surgical implications of colorectal cancer genetics. Surg Oncol Clin N Am. 2006;15(1):51-66, vi.
Rodriguez-Bigas, M. A., Chang, G. J., & Skibber, J. M. (2006). Surgical implications of colorectal cancer genetics. Surgical Oncology Clinics of North America, 15(1), 51-66, vi.
Rodriguez-Bigas MA, Chang GJ, Skibber JM. Surgical Implications of Colorectal Cancer Genetics. Surg Oncol Clin N Am. 2006;15(1):51-66, vi. PubMed PMID: 16389150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgical implications of colorectal cancer genetics. AU - Rodriguez-Bigas,Miguel A, AU - Chang,George J, AU - Skibber,John M, PY - 2006/1/4/pubmed PY - 2006/4/21/medline PY - 2006/1/4/entrez SP - 51-66, vi JF - Surgical oncology clinics of North America JO - Surg Oncol Clin N Am VL - 15 IS - 1 N2 - The applications of genetics in colorectal cancer are not limited to identifying germ-line mutations in genetically predisposed individuals. Reports on the use of molecular genetic markers as prognostic factors and for assessing the response to therapy are common in the literature. As the primary caregiver in the majority of these cases, the surgeon needs a basic knowledge of colorectal genetics and their implications to the patient and the patient's family. This article discusses a practical approach for some of the issues likely to be encountered by the surgeon. SN - 1055-3207 UR - https://www.unboundmedicine.com/medline/citation/16389150/Surgical_implications_of_colorectal_cancer_genetics_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1055-3207(05)00062-1 DB - PRIME DP - Unbound Medicine ER -