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Prevalence of gastro-oesophageal reflux disease in Spain and associated factors.
Aliment Pharmacol Ther 2006; 23(1):175-84AP

Abstract

BACKGROUND

The prevalence of gastro-oesophageal reflux disease (GERD), has not been characterized in Spain. Aim To measure the prevalence of GERD in Spain, and the factors associated with it, by means of a primary care-based study.

METHODS

An epidemiological, multicentre, cross-sectional, population-based study. A self-administered questionnaire was sent out to randomly selected patients. Data were statistically analysed to provide the prevalence of GERD and to compare it with that of gastro-oesophageal reflux symptoms. Factors associated with GERD were studied using logistic regression models.

RESULTS

The response rate was 45%. The prevalence of GERD was 15% (95% CI: 13.2-16.2). When compared with gastro-oesophageal reflux symptoms patients, those with GERD experienced more intense symptoms (moderate-severe: 35% vs. 8%, P < 0.001) and suffered heartburn more frequently both at day and night (48% vs. 25%, P < 0.001) and for longer period of times (69% vs. 62%, P = 0.057). A body mass index of >25% (odds ratio: 1.07; 95% CI: 1.03-1.11) was the only independent variable associated with GERD. The risk of suffering GERD increases by 7% for each kg/m(2) that the body mass index increases.

CONCLUSIONS

The prevalence of GERD among the Spanish population is 15%. Body mass index is the only risk factor significantly associated with GERD.

Authors+Show Affiliations

Gastroenterology Service, Hospital La Fe, Valencia, Spain. jponceg@medynet.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16393295

Citation

Ponce, J, et al. "Prevalence of Gastro-oesophageal Reflux Disease in Spain and Associated Factors." Alimentary Pharmacology & Therapeutics, vol. 23, no. 1, 2006, pp. 175-84.
Ponce J, Vegazo O, Beltrán B, et al. Prevalence of gastro-oesophageal reflux disease in Spain and associated factors. Aliment Pharmacol Ther. 2006;23(1):175-84.
Ponce, J., Vegazo, O., Beltrán, B., Jiménez, J., Zapardiel, J., Calle, D., & Piqué, J. M. (2006). Prevalence of gastro-oesophageal reflux disease in Spain and associated factors. Alimentary Pharmacology & Therapeutics, 23(1), pp. 175-84.
Ponce J, et al. Prevalence of Gastro-oesophageal Reflux Disease in Spain and Associated Factors. Aliment Pharmacol Ther. 2006 Jan 1;23(1):175-84. PubMed PMID: 16393295.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of gastro-oesophageal reflux disease in Spain and associated factors. AU - Ponce,J, AU - Vegazo,O, AU - Beltrán,B, AU - Jiménez,J, AU - Zapardiel,J, AU - Calle,D, AU - Piqué,J M, AU - ,, PY - 2006/1/6/pubmed PY - 2006/5/4/medline PY - 2006/1/6/entrez SP - 175 EP - 84 JF - Alimentary pharmacology & therapeutics JO - Aliment. Pharmacol. Ther. VL - 23 IS - 1 N2 - BACKGROUND: The prevalence of gastro-oesophageal reflux disease (GERD), has not been characterized in Spain. Aim To measure the prevalence of GERD in Spain, and the factors associated with it, by means of a primary care-based study. METHODS: An epidemiological, multicentre, cross-sectional, population-based study. A self-administered questionnaire was sent out to randomly selected patients. Data were statistically analysed to provide the prevalence of GERD and to compare it with that of gastro-oesophageal reflux symptoms. Factors associated with GERD were studied using logistic regression models. RESULTS: The response rate was 45%. The prevalence of GERD was 15% (95% CI: 13.2-16.2). When compared with gastro-oesophageal reflux symptoms patients, those with GERD experienced more intense symptoms (moderate-severe: 35% vs. 8%, P < 0.001) and suffered heartburn more frequently both at day and night (48% vs. 25%, P < 0.001) and for longer period of times (69% vs. 62%, P = 0.057). A body mass index of >25% (odds ratio: 1.07; 95% CI: 1.03-1.11) was the only independent variable associated with GERD. The risk of suffering GERD increases by 7% for each kg/m(2) that the body mass index increases. CONCLUSIONS: The prevalence of GERD among the Spanish population is 15%. Body mass index is the only risk factor significantly associated with GERD. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/16393295/Prevalence_of_gastro_oesophageal_reflux_disease_in_Spain_and_associated_factors_ L2 - https://doi.org/10.1111/j.1365-2036.2006.02733.x DB - PRIME DP - Unbound Medicine ER -