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Body mass index is inversely related to mortality in older people after adjustment for waist circumference.
J Am Geriatr Soc 2005; 53(12):2112-8JA

Abstract

OBJECTIVES

To examine the individual and combined influence of body mass index (BMI) and waist circumference (WC) on mortality risk in older people.

DESIGN

Longitudinal cohort study.

SETTING

Cardiovascular Health Study, a longitudinal study of cardiovascular disease and its risk factors in older people.

PARTICIPANTS

Five thousand two hundred men and women aged 65 and older.

MEASUREMENTS

BMI and WC were measured at baseline. The risks of all-cause mortality associated with BMI and WC were examined using Cox proportional hazards models over 9 years of follow-up.

RESULTS

When examined individually, BMI and WC were both negative predictors of mortality, but when BMI and WC were examined simultaneously, BMI was a negative predictor of mortality, whereas WC was a positive predictor of mortality. After controlling for WC, mortality risk decreased 21% for every standard deviation increase in BMI. After controlling for BMI, mortality risk increased 13% for every standard deviation increase in WC. The patterns of associations were consistent by sex, age, and disease status.

CONCLUSION

Higher BMI values indicated a lower mortality risk once the risk attributable to WC was accounted for, whereas higher WC values indicate a higher mortality risk once the risk attributable to BMI was accounted for. Both BMI and WC should be measured in the clinical setting, but in older adults higher BMI is associated with lower mortality rates.

Authors+Show Affiliations

School of Physical and Health Education, Queen's University, Kingston, Ontario, Canada. janssen@post.queensu.caNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16398895

Citation

Janssen, Ian, et al. "Body Mass Index Is Inversely Related to Mortality in Older People After Adjustment for Waist Circumference." Journal of the American Geriatrics Society, vol. 53, no. 12, 2005, pp. 2112-8.
Janssen I, Katzmarzyk PT, Ross R. Body mass index is inversely related to mortality in older people after adjustment for waist circumference. J Am Geriatr Soc. 2005;53(12):2112-8.
Janssen, I., Katzmarzyk, P. T., & Ross, R. (2005). Body mass index is inversely related to mortality in older people after adjustment for waist circumference. Journal of the American Geriatrics Society, 53(12), pp. 2112-8.
Janssen I, Katzmarzyk PT, Ross R. Body Mass Index Is Inversely Related to Mortality in Older People After Adjustment for Waist Circumference. J Am Geriatr Soc. 2005;53(12):2112-8. PubMed PMID: 16398895.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Body mass index is inversely related to mortality in older people after adjustment for waist circumference. AU - Janssen,Ian, AU - Katzmarzyk,Peter T, AU - Ross,Robert, PY - 2006/1/10/pubmed PY - 2006/2/9/medline PY - 2006/1/10/entrez SP - 2112 EP - 8 JF - Journal of the American Geriatrics Society JO - J Am Geriatr Soc VL - 53 IS - 12 N2 - OBJECTIVES: To examine the individual and combined influence of body mass index (BMI) and waist circumference (WC) on mortality risk in older people. DESIGN: Longitudinal cohort study. SETTING: Cardiovascular Health Study, a longitudinal study of cardiovascular disease and its risk factors in older people. PARTICIPANTS: Five thousand two hundred men and women aged 65 and older. MEASUREMENTS: BMI and WC were measured at baseline. The risks of all-cause mortality associated with BMI and WC were examined using Cox proportional hazards models over 9 years of follow-up. RESULTS: When examined individually, BMI and WC were both negative predictors of mortality, but when BMI and WC were examined simultaneously, BMI was a negative predictor of mortality, whereas WC was a positive predictor of mortality. After controlling for WC, mortality risk decreased 21% for every standard deviation increase in BMI. After controlling for BMI, mortality risk increased 13% for every standard deviation increase in WC. The patterns of associations were consistent by sex, age, and disease status. CONCLUSION: Higher BMI values indicated a lower mortality risk once the risk attributable to WC was accounted for, whereas higher WC values indicate a higher mortality risk once the risk attributable to BMI was accounted for. Both BMI and WC should be measured in the clinical setting, but in older adults higher BMI is associated with lower mortality rates. SN - 0002-8614 UR - https://www.unboundmedicine.com/medline/citation/16398895/Body_mass_index_is_inversely_related_to_mortality_in_older_people_after_adjustment_for_waist_circumference_ L2 - https://doi.org/10.1111/j.1532-5415.2005.00505.x DB - PRIME DP - Unbound Medicine ER -