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Gastroesophageal reflux disease and Helicobacter pylori: lack of influence of infection on oesophageal manometric, 3-hour postprandial pHmetric and endoscopic findings.
Rom J Gastroenterol 2005; 14(4):351-5RJ

Abstract

AIM

To investigate the relationship between Helicobacter pylori and gastro-oesophageal reflux disease according to manometric and pHmetric findings.

METHOD

Fifty-nine consecutive patients with reflux symptoms and endoscopic evidence of mild oesophagitis, were recruited. Manometry and ambulatory pHmetry were performed in all patients, as well as the 3-hour postprandial pHmetry, as a more flexible and well tolerable test.

RESULTS

There were no significant differences between Helicobacter pylori positive and negative patients regarding age, sex ratio and endoscopic severity of oesophagitis. There was no difference in prevalence of abnormal oesophageal peristalsis between the two groups (Fisher's exact test, p=NS). Differences were also not found regarding lower oesophageal sphincter pressure between the two groups (mean PLOS 12.86+/-4.39 mmHg and 13.1+/-4.61 mmHg respectively; p=0.840). Finally, the mean values of DeMeester score were 60.38+/-48.04 and 67.64+/-51.04 respectively (p=0.576).

CONCLUSION

Helicobacter pylori infection does not influence oesophageal peristalsis, the lower oesophageal sphincter pressure and the acidity of refluxates into the oesophageal lumen, in patients with established gastro-oesophageal reflux disease (esophagitis grade A and B).

Authors+Show Affiliations

Medical School Democritus University of Thrace, Alexandroupolis, Greece. gut@in.grNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16400350

Citation

Moschos, John, et al. "Gastroesophageal Reflux Disease and Helicobacter Pylori: Lack of Influence of Infection On Oesophageal Manometric, 3-hour Postprandial pHmetric and Endoscopic Findings." Romanian Journal of Gastroenterology, vol. 14, no. 4, 2005, pp. 351-5.
Moschos J, Kouklakis G, Lyratzopoulos N, et al. Gastroesophageal reflux disease and Helicobacter pylori: lack of influence of infection on oesophageal manometric, 3-hour postprandial pHmetric and endoscopic findings. Rom J Gastroenterol. 2005;14(4):351-5.
Moschos, J., Kouklakis, G., Lyratzopoulos, N., Efremidou, E., Maltezos, E., & Minopoulos, G. (2005). Gastroesophageal reflux disease and Helicobacter pylori: lack of influence of infection on oesophageal manometric, 3-hour postprandial pHmetric and endoscopic findings. Romanian Journal of Gastroenterology, 14(4), pp. 351-5.
Moschos J, et al. Gastroesophageal Reflux Disease and Helicobacter Pylori: Lack of Influence of Infection On Oesophageal Manometric, 3-hour Postprandial pHmetric and Endoscopic Findings. Rom J Gastroenterol. 2005;14(4):351-5. PubMed PMID: 16400350.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastroesophageal reflux disease and Helicobacter pylori: lack of influence of infection on oesophageal manometric, 3-hour postprandial pHmetric and endoscopic findings. AU - Moschos,John, AU - Kouklakis,George, AU - Lyratzopoulos,Nikolaos, AU - Efremidou,Eleni, AU - Maltezos,Eustratios, AU - Minopoulos,George, PY - 2006/1/10/pubmed PY - 2006/2/24/medline PY - 2006/1/10/entrez SP - 351 EP - 5 JF - Romanian journal of gastroenterology JO - Rom J Gastroenterol VL - 14 IS - 4 N2 - AIM: To investigate the relationship between Helicobacter pylori and gastro-oesophageal reflux disease according to manometric and pHmetric findings. METHOD: Fifty-nine consecutive patients with reflux symptoms and endoscopic evidence of mild oesophagitis, were recruited. Manometry and ambulatory pHmetry were performed in all patients, as well as the 3-hour postprandial pHmetry, as a more flexible and well tolerable test. RESULTS: There were no significant differences between Helicobacter pylori positive and negative patients regarding age, sex ratio and endoscopic severity of oesophagitis. There was no difference in prevalence of abnormal oesophageal peristalsis between the two groups (Fisher's exact test, p=NS). Differences were also not found regarding lower oesophageal sphincter pressure between the two groups (mean PLOS 12.86+/-4.39 mmHg and 13.1+/-4.61 mmHg respectively; p=0.840). Finally, the mean values of DeMeester score were 60.38+/-48.04 and 67.64+/-51.04 respectively (p=0.576). CONCLUSION: Helicobacter pylori infection does not influence oesophageal peristalsis, the lower oesophageal sphincter pressure and the acidity of refluxates into the oesophageal lumen, in patients with established gastro-oesophageal reflux disease (esophagitis grade A and B). SN - 1221-4167 UR - https://www.unboundmedicine.com/medline/citation/16400350/Gastroesophageal_reflux_disease_and_Helicobacter_pylori:_lack_of_influence_of_infection_on_oesophageal_manometric_3_hour_postprandial_pHmetric_and_endoscopic_findings_ L2 - http://www.jgld.ro/2005/4/4.html DB - PRIME DP - Unbound Medicine ER -