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[Statins in chronic renal disease].
Arq Bras Cardiol. 2005 Oct; 85 Suppl 5:45-9.AB

Abstract

Hypertriglyceridemia and low HDL-c are common features in patients with chronic renal failure. Cardiovascular mortality is substantially increased in the presence of chronic renal disease (10-20 times higher). There is evidence from clinical trials with statins suggesting their protective role in the progression of renal disease. In addition, reduced rates of non-fatal myocardial infarction and cardiac mortality were seen after renal transplant in patients receiving fluvastatin. However, a recent study with atorvastatin failed to demonstrate reduction in cardiovascular morbidity and mortality among diabetic patients on hemodialysis therapy. Ongoing trials will define the precise role of statins in this subset of patients.

Authors+Show Affiliations

Ferreira SR
Faculdade de Medicina, PUC de Campinas.
Rocha AM
No affiliation info available
Saraiva JF
No affiliation info available

MeSH

BrazilCardiovascular DiseasesDyslipidemiasHumansHydroxymethylglutaryl-CoA Reductase InhibitorsKidneyKidney Failure, ChronicLiver TransplantationRenal DialysisRisk Factors

Pub Type(s)

English Abstract
Journal Article

Language

por

PubMed ID

16400399

Citation

Ferreira, Soraia R C., et al. "[Statins in Chronic Renal Disease]." Arquivos Brasileiros De Cardiologia, vol. 85 Suppl 5, 2005, pp. 45-9.
Ferreira SR, Rocha AM, Saraiva JF. [Statins in chronic renal disease]. Arq Bras Cardiol. 2005;85 Suppl 5:45-9.
Ferreira, S. R., Rocha, A. M., & Saraiva, J. F. (2005). [Statins in chronic renal disease]. Arquivos Brasileiros De Cardiologia, 85 Suppl 5, 45-9.
Ferreira SR, Rocha AM, Saraiva JF. [Statins in Chronic Renal Disease]. Arq Bras Cardiol. 2005;85 Suppl 5:45-9. PubMed PMID: 16400399.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Statins in chronic renal disease]. AU - Ferreira,Soraia R C, AU - Rocha,Aloísio M, AU - Saraiva,José Francisco K, Y1 - 2006/01/02/ PY - 2006/1/10/pubmed PY - 2006/5/12/medline PY - 2006/1/10/entrez SP - 45 EP - 9 JF - Arquivos brasileiros de cardiologia JO - Arq Bras Cardiol VL - 85 Suppl 5 N2 - Hypertriglyceridemia and low HDL-c are common features in patients with chronic renal failure. Cardiovascular mortality is substantially increased in the presence of chronic renal disease (10-20 times higher). There is evidence from clinical trials with statins suggesting their protective role in the progression of renal disease. In addition, reduced rates of non-fatal myocardial infarction and cardiac mortality were seen after renal transplant in patients receiving fluvastatin. However, a recent study with atorvastatin failed to demonstrate reduction in cardiovascular morbidity and mortality among diabetic patients on hemodialysis therapy. Ongoing trials will define the precise role of statins in this subset of patients. SN - 0066-782X UR - https://www.unboundmedicine.com/medline/citation/16400399/[Statins_in_chronic_renal_disease]_ DB - PRIME DP - Unbound Medicine ER -