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NC-stat sensory nerve conduction studies in the median and ulnar nerves of symptomatic patients.
Clin Neurophysiol. 2006 Feb; 117(2):405-13.CN

Abstract

OBJECTIVE

This study evaluated validity and reliability of automated median and ulnar sensory nerve conduction study (NCS) measurements by the NC-stat.

METHODS

Median and ulnar distal sensory latencies (DSL) and amplitudes (SNAP) were measured in sixty subjects with the NC-stat and by a neurologist (reference) using traditional instrumentation. The median-ulnar DSL differences (MUD) was calculated. Validity was quantified by the Pearson correlation. Reliability was evaluated by the intraclass correlation coefficient (ICC), Bland-Altman analysis, and inter-rater agreement of MUD abnormalities.

RESULTS

As a result of differences in electrode placement, NC-stat and reference mean values had systematic differences. The correlation ranged from 0.70 (ulnar DSL) to 0.91 (median DSL). The ICC ranged from 0.69 (ulnar DSL) to 0.91 (median DSL). In Bland-Altman analysis of DSLs, NC-stat measurements had a bias of 0.56 ms (median) and 0.31 ms (ulnar) and precision of 0.31 and 0.30 ms. Inter-rater agreement for MUD abnormalities was 93.8% (raw) and 0.80 (Kappa).

CONCLUSIONS

NC-stat validity and reliability metrics were similar to traditional NCS. Use of the NC-stat would require applicable reference ranges.

SIGNIFICANCE

NC-stat median and ulnar NCS are valid and reliable. This device may be useful for increasing availability of NCS when clinically appropriate.

Authors+Show Affiliations

NEUROMetrix Inc., 62 Fourth Avenue, Waltham, MA 02451, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16403673

Citation

Kong, Xuan, et al. "NC-stat Sensory Nerve Conduction Studies in the Median and Ulnar Nerves of Symptomatic Patients." Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, vol. 117, no. 2, 2006, pp. 405-13.
Kong X, Gozani SN, Hayes MT, et al. NC-stat sensory nerve conduction studies in the median and ulnar nerves of symptomatic patients. Clin Neurophysiol. 2006;117(2):405-13.
Kong, X., Gozani, S. N., Hayes, M. T., & Weinberg, D. H. (2006). NC-stat sensory nerve conduction studies in the median and ulnar nerves of symptomatic patients. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 117(2), 405-13.
Kong X, et al. NC-stat Sensory Nerve Conduction Studies in the Median and Ulnar Nerves of Symptomatic Patients. Clin Neurophysiol. 2006;117(2):405-13. PubMed PMID: 16403673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - NC-stat sensory nerve conduction studies in the median and ulnar nerves of symptomatic patients. AU - Kong,Xuan, AU - Gozani,Shai N, AU - Hayes,Michael T, AU - Weinberg,David H, Y1 - 2006/01/03/ PY - 2005/08/08/received PY - 2005/09/23/revised PY - 2005/10/22/accepted PY - 2006/1/13/pubmed PY - 2006/5/10/medline PY - 2006/1/13/entrez SP - 405 EP - 13 JF - Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology JO - Clin Neurophysiol VL - 117 IS - 2 N2 - OBJECTIVE: This study evaluated validity and reliability of automated median and ulnar sensory nerve conduction study (NCS) measurements by the NC-stat. METHODS: Median and ulnar distal sensory latencies (DSL) and amplitudes (SNAP) were measured in sixty subjects with the NC-stat and by a neurologist (reference) using traditional instrumentation. The median-ulnar DSL differences (MUD) was calculated. Validity was quantified by the Pearson correlation. Reliability was evaluated by the intraclass correlation coefficient (ICC), Bland-Altman analysis, and inter-rater agreement of MUD abnormalities. RESULTS: As a result of differences in electrode placement, NC-stat and reference mean values had systematic differences. The correlation ranged from 0.70 (ulnar DSL) to 0.91 (median DSL). The ICC ranged from 0.69 (ulnar DSL) to 0.91 (median DSL). In Bland-Altman analysis of DSLs, NC-stat measurements had a bias of 0.56 ms (median) and 0.31 ms (ulnar) and precision of 0.31 and 0.30 ms. Inter-rater agreement for MUD abnormalities was 93.8% (raw) and 0.80 (Kappa). CONCLUSIONS: NC-stat validity and reliability metrics were similar to traditional NCS. Use of the NC-stat would require applicable reference ranges. SIGNIFICANCE: NC-stat median and ulnar NCS are valid and reliable. This device may be useful for increasing availability of NCS when clinically appropriate. SN - 1388-2457 UR - https://www.unboundmedicine.com/medline/citation/16403673/NC_stat_sensory_nerve_conduction_studies_in_the_median_and_ulnar_nerves_of_symptomatic_patients_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1388-2457(05)00433-5 DB - PRIME DP - Unbound Medicine ER -