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Antiinflammatory activity of Sambucus ebulus hexane extracts.
Fitoterapia. 2006 Feb; 77(2):146-8.F

Abstract

Hexane extracts of aerial parts (flowered browes), leaves and roots of Sambucus ebulus were investigated for their antiinflammatory activity in rats. Aerial parts and roots extracts produced statistically significant and dose dependent inhibition of edema induced by carrageenan at all doses when compared to the control groups. On the contrary, hexane extract of leaves did not show any activity up to 600 mg/kg i.p. The highest activity was showed in the aerial parts and roots that at 600 mg/kg i.p. inhibited inflammation by ca. 80% (78% for diclofenac at 100 mg /kg i.p.). No extracts exhibit toxicity when injected up to 2 g/ kg intraperitoneally in mice.

Authors+Show Affiliations

Department of Medicinal Chemistry, School of Pharmacy, Medical Sciences University of Mazandaran, Sari, Iran. zadeh20@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16406693

Citation

Ebrahimzadeh, M A., et al. "Antiinflammatory Activity of Sambucus Ebulus Hexane Extracts." Fitoterapia, vol. 77, no. 2, 2006, pp. 146-8.
Ebrahimzadeh MA, Mahmoudi M, Salimi E. Antiinflammatory activity of Sambucus ebulus hexane extracts. Fitoterapia. 2006;77(2):146-8.
Ebrahimzadeh, M. A., Mahmoudi, M., & Salimi, E. (2006). Antiinflammatory activity of Sambucus ebulus hexane extracts. Fitoterapia, 77(2), 146-8.
Ebrahimzadeh MA, Mahmoudi M, Salimi E. Antiinflammatory Activity of Sambucus Ebulus Hexane Extracts. Fitoterapia. 2006;77(2):146-8. PubMed PMID: 16406693.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antiinflammatory activity of Sambucus ebulus hexane extracts. AU - Ebrahimzadeh,M A, AU - Mahmoudi,M, AU - Salimi,E, Y1 - 2006/01/09/ PY - 2005/06/24/received PY - 2005/11/17/accepted PY - 2006/1/13/pubmed PY - 2006/5/4/medline PY - 2006/1/13/entrez SP - 146 EP - 8 JF - Fitoterapia JO - Fitoterapia VL - 77 IS - 2 N2 - Hexane extracts of aerial parts (flowered browes), leaves and roots of Sambucus ebulus were investigated for their antiinflammatory activity in rats. Aerial parts and roots extracts produced statistically significant and dose dependent inhibition of edema induced by carrageenan at all doses when compared to the control groups. On the contrary, hexane extract of leaves did not show any activity up to 600 mg/kg i.p. The highest activity was showed in the aerial parts and roots that at 600 mg/kg i.p. inhibited inflammation by ca. 80% (78% for diclofenac at 100 mg /kg i.p.). No extracts exhibit toxicity when injected up to 2 g/ kg intraperitoneally in mice. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/16406693/Antiinflammatory_activity_of_Sambucus_ebulus_hexane_extracts_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(05)00240-6 DB - PRIME DP - Unbound Medicine ER -