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[Optical penetrating keratoplasty in eyes with severe keratomycosis after therapeutic keratoplasty].
Zhonghua Yan Ke Za Zhi 2005; 41(12):1103-6ZY

Abstract

OBJECTIVE

To observe and evaluate secondary optical penetrating keratoplasty (PKP) in the eyes with severe keratomycosis after therapeutic keratoplasty using cryopreserved donor tissue.

METHOD

There were 35 eyes in 35 cases for whom therapeutic PKP using cryopreserved donor tissue had been carried out to treat severe fungal keratitis. At least 6 months after the PKP, when the fungal infection had been eradicated and ocular inflammation had resolved, a secondary optical penetrating keratoplasty was further performed for visual rehabilitation. If the crystal lens was found to be opaque, it was also simultaneously removed through extracapsular cataract removal with an IOL implantation. Surgical or postoperative complications, visual outcome, graft rejection episode, and graft survival were analyzed.

RESULTS

Among 35 eyes, 18 eyes received optical PKP only, and 17 received combined optical PKP with ECCE and IOL implantation. During the follow-up period of 6.8 - 36.8 (15.7 +/- 7.6) months after optical PKP, 3 eyes experienced graft failure due to immunologic rejection and 32 retained clear grafts. Postoperative visual acuity was 0.4 or better in 24 eyes, and 0.1 or better in 32 eyes, and less than 0.1 in 3 eyes.

CONCLUSIONS

Optical PKP performed in the eyes after therapeutic PKP due to severe fungal keratitis can recover satisfactory visual acuity, with low frequency of graft rejection, long-term graft survival and few complications.

Authors+Show Affiliations

Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

16409764

Citation

Zhou, Ping, et al. "[Optical Penetrating Keratoplasty in Eyes With Severe Keratomycosis After Therapeutic Keratoplasty]." [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, vol. 41, no. 12, 2005, pp. 1103-6.
Zhou P, Yao YF, Qiu WY, et al. [Optical penetrating keratoplasty in eyes with severe keratomycosis after therapeutic keratoplasty]. Zhonghua Yan Ke Za Zhi. 2005;41(12):1103-6.
Zhou, P., Yao, Y. F., Qiu, W. Y., Zhang, Y. M., & Zhang, B. (2005). [Optical penetrating keratoplasty in eyes with severe keratomycosis after therapeutic keratoplasty]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology, 41(12), pp. 1103-6.
Zhou P, et al. [Optical Penetrating Keratoplasty in Eyes With Severe Keratomycosis After Therapeutic Keratoplasty]. Zhonghua Yan Ke Za Zhi. 2005;41(12):1103-6. PubMed PMID: 16409764.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Optical penetrating keratoplasty in eyes with severe keratomycosis after therapeutic keratoplasty]. AU - Zhou,Ping, AU - Yao,Yu-feng, AU - Qiu,Wen-ya, AU - Zhang,Yong-ming, AU - Zhang,Bei, PY - 2006/1/18/pubmed PY - 2009/12/24/medline PY - 2006/1/18/entrez SP - 1103 EP - 6 JF - [Zhonghua yan ke za zhi] Chinese journal of ophthalmology JO - Zhonghua Yan Ke Za Zhi VL - 41 IS - 12 N2 - OBJECTIVE: To observe and evaluate secondary optical penetrating keratoplasty (PKP) in the eyes with severe keratomycosis after therapeutic keratoplasty using cryopreserved donor tissue. METHOD: There were 35 eyes in 35 cases for whom therapeutic PKP using cryopreserved donor tissue had been carried out to treat severe fungal keratitis. At least 6 months after the PKP, when the fungal infection had been eradicated and ocular inflammation had resolved, a secondary optical penetrating keratoplasty was further performed for visual rehabilitation. If the crystal lens was found to be opaque, it was also simultaneously removed through extracapsular cataract removal with an IOL implantation. Surgical or postoperative complications, visual outcome, graft rejection episode, and graft survival were analyzed. RESULTS: Among 35 eyes, 18 eyes received optical PKP only, and 17 received combined optical PKP with ECCE and IOL implantation. During the follow-up period of 6.8 - 36.8 (15.7 +/- 7.6) months after optical PKP, 3 eyes experienced graft failure due to immunologic rejection and 32 retained clear grafts. Postoperative visual acuity was 0.4 or better in 24 eyes, and 0.1 or better in 32 eyes, and less than 0.1 in 3 eyes. CONCLUSIONS: Optical PKP performed in the eyes after therapeutic PKP due to severe fungal keratitis can recover satisfactory visual acuity, with low frequency of graft rejection, long-term graft survival and few complications. SN - 0412-4081 UR - https://www.unboundmedicine.com/medline/citation/16409764/[Optical_penetrating_keratoplasty_in_eyes_with_severe_keratomycosis_after_therapeutic_keratoplasty]_ DB - PRIME DP - Unbound Medicine ER -