Tags

Type your tag names separated by a space and hit enter

Use of an Italian version of the telephone interview for cognitive status in Alzheimer's disease.
Int J Geriatr Psychiatry. 2006 Feb; 21(2):126-33.IJ

Abstract

OBJECTIVES

Validation of an Italian version of the Telephone Interview for Cognitive Status (I-TICS).

METHODS

Telephone administration of the I-TICS within 6 weeks of face-to-face testing with the Mini Mental State Examination (MMSE), in Probable Alzheimer's disease (AD) patients and healthy controls. Two hundred and seven consecutive outpatients with cognitive impairment were recruited from Dementia Clinic of University Campus BioMedico. Of these, 45 probable AD patients with complete data were analyzed. Other dementias, Mild Cognitive Impairment (MCI), and patients with incomplete data were excluded. The control sample consisted of 64 age- and sex-matched healthy subjects. For diagnosis, an extensive clinical evaluation, laboratory testing, brain imaging, EEG, neuropsychological battery and a depression scale were used. For I-TICS validation, telephone I-TICS and face-to-face MMSE were administered.

RESULTS

The I-TICS correlated highly and linearly with the MMSE (Pearson's r=0.904). Conversion equations are provided. Sensitivity and specificity were similar between tests (area under curve=0.894 for the I-TICS; 0.966 for the MMSE). I-TICS sensitivity was 84% and specificity 86% at a cut-off score of 28. No significant difference in accuracy with the MMSE was present. Total agreement between I-TICS and MMSE was 'substantial' at 86% (Cohen's K=0.717). Repeated testing in a subset of patients showed a disease progression related decrease of 4.2 points/year (t=2.664; p=0.018) in I-TICS scores.

CONCLUSION

The I-TICS is a valid instrument in clinical and research screening and monitoring of AD. Potential applications in other dementias and MCI are worth further studies.

Authors+Show Affiliations

Clinical Neurology, University Campus BioMedico, Rome, Italy. g.dalforno@unicampus.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

16416467

Citation

Dal Forno, Gloria, et al. "Use of an Italian Version of the Telephone Interview for Cognitive Status in Alzheimer's Disease." International Journal of Geriatric Psychiatry, vol. 21, no. 2, 2006, pp. 126-33.
Dal Forno G, Chiovenda P, Bressi F, et al. Use of an Italian version of the telephone interview for cognitive status in Alzheimer's disease. Int J Geriatr Psychiatry. 2006;21(2):126-33.
Dal Forno, G., Chiovenda, P., Bressi, F., Ferreri, F., Grossi, E., Brandt, J., Rossini, P. M., & Pasqualetti, P. (2006). Use of an Italian version of the telephone interview for cognitive status in Alzheimer's disease. International Journal of Geriatric Psychiatry, 21(2), 126-33.
Dal Forno G, et al. Use of an Italian Version of the Telephone Interview for Cognitive Status in Alzheimer's Disease. Int J Geriatr Psychiatry. 2006;21(2):126-33. PubMed PMID: 16416467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of an Italian version of the telephone interview for cognitive status in Alzheimer's disease. AU - Dal Forno,Gloria, AU - Chiovenda,Paola, AU - Bressi,Federica, AU - Ferreri,Florinda, AU - Grossi,Enzo, AU - Brandt,Jason, AU - Rossini,Paolo Maria, AU - Pasqualetti,Patrizio, PY - 2006/1/18/pubmed PY - 2006/8/2/medline PY - 2006/1/18/entrez SP - 126 EP - 33 JF - International journal of geriatric psychiatry JO - Int J Geriatr Psychiatry VL - 21 IS - 2 N2 - OBJECTIVES: Validation of an Italian version of the Telephone Interview for Cognitive Status (I-TICS). METHODS: Telephone administration of the I-TICS within 6 weeks of face-to-face testing with the Mini Mental State Examination (MMSE), in Probable Alzheimer's disease (AD) patients and healthy controls. Two hundred and seven consecutive outpatients with cognitive impairment were recruited from Dementia Clinic of University Campus BioMedico. Of these, 45 probable AD patients with complete data were analyzed. Other dementias, Mild Cognitive Impairment (MCI), and patients with incomplete data were excluded. The control sample consisted of 64 age- and sex-matched healthy subjects. For diagnosis, an extensive clinical evaluation, laboratory testing, brain imaging, EEG, neuropsychological battery and a depression scale were used. For I-TICS validation, telephone I-TICS and face-to-face MMSE were administered. RESULTS: The I-TICS correlated highly and linearly with the MMSE (Pearson's r=0.904). Conversion equations are provided. Sensitivity and specificity were similar between tests (area under curve=0.894 for the I-TICS; 0.966 for the MMSE). I-TICS sensitivity was 84% and specificity 86% at a cut-off score of 28. No significant difference in accuracy with the MMSE was present. Total agreement between I-TICS and MMSE was 'substantial' at 86% (Cohen's K=0.717). Repeated testing in a subset of patients showed a disease progression related decrease of 4.2 points/year (t=2.664; p=0.018) in I-TICS scores. CONCLUSION: The I-TICS is a valid instrument in clinical and research screening and monitoring of AD. Potential applications in other dementias and MCI are worth further studies. SN - 0885-6230 UR - https://www.unboundmedicine.com/medline/citation/16416467/Use_of_an_Italian_version_of_the_telephone_interview_for_cognitive_status_in_Alzheimer's_disease_ L2 - https://doi.org/10.1002/gps.1435 DB - PRIME DP - Unbound Medicine ER -