Tags

Type your tag names separated by a space and hit enter

Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC).
Int J Cancer 2006; 118(12):3133-9IJ

Abstract

We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and RCC risk were observed despite a wide range of intake. The estimated relative risks (95% confidence intervals [CI]) in men and women combined were 0.97 (0.85-1.11) per 40 g increase in vegetable intake, 1.03 (0.97-1.08) per 40 g increase in fruit intake and 1.02 (0.93-1.11) per 80 g increase in fruit and vegetable intake combined. Among the vegetable subtypes, an inverse association was observed for root vegetables (RR per 8 g increase: 0.88; 95% CI: 0.78-0.99). These results suggest that total consumption of fruits and vegetables is not related to risk of RCC, although we cannot exclude the possibility that very low consumption is related to higher risk. The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation.

Authors+Show Affiliations

Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16425278

Citation

Weikert, Steffen, et al. "Fruits and Vegetables and Renal Cell Carcinoma: Findings From the European Prospective Investigation Into Cancer and Nutrition (EPIC)." International Journal of Cancer, vol. 118, no. 12, 2006, pp. 3133-9.
Weikert S, Boeing H, Pischon T, et al. Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC). Int J Cancer. 2006;118(12):3133-9.
Weikert, S., Boeing, H., Pischon, T., Olsen, A., Tjonneland, A., Overvad, K., ... Riboli, E. (2006). Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC). International Journal of Cancer, 118(12), pp. 3133-9.
Weikert S, et al. Fruits and Vegetables and Renal Cell Carcinoma: Findings From the European Prospective Investigation Into Cancer and Nutrition (EPIC). Int J Cancer. 2006 Jun 15;118(12):3133-9. PubMed PMID: 16425278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC). AU - Weikert,Steffen, AU - Boeing,Heiner, AU - Pischon,Tobias, AU - Olsen,Anja, AU - Tjonneland,Anne, AU - Overvad,Kim, AU - Becker,Nikolaus, AU - Linseisen,Jacob, AU - Lahmann,Petra H, AU - Arvaniti,Athina, AU - Kassapa,Christina, AU - Trichoupoulou,Antonia, AU - Sieri,Sabina, AU - Palli,Domenico, AU - Tumino,Rosario, AU - Vineis,Paolo, AU - Panico,Salvatore, AU - van Gils,Carla H, AU - Peeters,Petra H M, AU - Bueno-de-Mesquita,H Bas, AU - Büchner,Frederike L, AU - Ljungberg,Börje, AU - Hallmans,Göran, AU - Berglund,Göran, AU - Wirfält,Elisabet, AU - Pera,Guillem, AU - Dorronsoro,Miren, AU - Gurrea,Aurelio Barricarte, AU - Navarro,Carmen, AU - Martinez,Carmen, AU - Quirós,J Ramón, AU - Allen,Naomi, AU - Roddam,Andrew, AU - Bingham,Sheila, AU - Jenab,Mazda, AU - Slimani,Nadia, AU - Norat,Teresa, AU - Riboli,Elio, PY - 2006/1/21/pubmed PY - 2006/5/24/medline PY - 2006/1/21/entrez SP - 3133 EP - 9 JF - International journal of cancer JO - Int. J. Cancer VL - 118 IS - 12 N2 - We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and RCC risk were observed despite a wide range of intake. The estimated relative risks (95% confidence intervals [CI]) in men and women combined were 0.97 (0.85-1.11) per 40 g increase in vegetable intake, 1.03 (0.97-1.08) per 40 g increase in fruit intake and 1.02 (0.93-1.11) per 80 g increase in fruit and vegetable intake combined. Among the vegetable subtypes, an inverse association was observed for root vegetables (RR per 8 g increase: 0.88; 95% CI: 0.78-0.99). These results suggest that total consumption of fruits and vegetables is not related to risk of RCC, although we cannot exclude the possibility that very low consumption is related to higher risk. The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation. SN - 0020-7136 UR - https://www.unboundmedicine.com/medline/citation/16425278/Fruits_and_vegetables_and_renal_cell_carcinoma:_findings_from_the_European_prospective_investigation_into_cancer_and_nutrition__EPIC__ L2 - https://doi.org/10.1002/ijc.21765 DB - PRIME DP - Unbound Medicine ER -