Tags

Type your tag names separated by a space and hit enter

Thymic stromal lymphopoietin: master switch for allergic inflammation.
J Exp Med. 2006 Feb 20; 203(2):269-73.JE

Abstract

Thymic stromal lymphopoietin (TSLP) is an interleukin (IL) 7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses. TSLP is highly expressed by keratinocytes in skin lesions of patients with atopic dermatitis and is associated with dendritic cell activation in situ, suggesting that TSLP might be a master switch for allergic inflammation at the epithelial cell-dendritic cell interface. New reports now establish a direct link between TSLP expression and the pathogenesis of atopic dermatitis and asthma in vivo, and begin to reveal the molecular mechanisms underlying TSLP-induced allergic inflammation.

Authors+Show Affiliations

Department of Immunology and Center of Cancer Immunology Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. yjliu@mdanderson.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16432252

Citation

Liu, Yong-Jun. "Thymic Stromal Lymphopoietin: Master Switch for Allergic Inflammation." The Journal of Experimental Medicine, vol. 203, no. 2, 2006, pp. 269-73.
Liu YJ. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med. 2006;203(2):269-73.
Liu, Y. J. (2006). Thymic stromal lymphopoietin: master switch for allergic inflammation. The Journal of Experimental Medicine, 203(2), 269-73.
Liu YJ. Thymic Stromal Lymphopoietin: Master Switch for Allergic Inflammation. J Exp Med. 2006 Feb 20;203(2):269-73. PubMed PMID: 16432252.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thymic stromal lymphopoietin: master switch for allergic inflammation. A1 - Liu,Yong-Jun, Y1 - 2006/01/23/ PY - 2006/1/25/pubmed PY - 2006/4/4/medline PY - 2006/1/25/entrez SP - 269 EP - 73 JF - The Journal of experimental medicine JO - J Exp Med VL - 203 IS - 2 N2 - Thymic stromal lymphopoietin (TSLP) is an interleukin (IL) 7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses. TSLP is highly expressed by keratinocytes in skin lesions of patients with atopic dermatitis and is associated with dendritic cell activation in situ, suggesting that TSLP might be a master switch for allergic inflammation at the epithelial cell-dendritic cell interface. New reports now establish a direct link between TSLP expression and the pathogenesis of atopic dermatitis and asthma in vivo, and begin to reveal the molecular mechanisms underlying TSLP-induced allergic inflammation. SN - 0022-1007 UR - https://www.unboundmedicine.com/medline/citation/16432252/Thymic_stromal_lymphopoietin:_master_switch_for_allergic_inflammation_ L2 - https://rupress.org/jem/article-lookup/doi/10.1084/jem.20051745 DB - PRIME DP - Unbound Medicine ER -