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Helicobacter pylori infection is probably the cause of chronic idiopathic neutropenia (CIN)-associated splenomegaly.
Am J Hematol 2006; 81(2):142-4AJ

Abstract

Splenic volume and Helicobacter pylori (H. pylori) infection were evaluated in 67 patients with chronic idiopathic neutropenia (CIN) and 39 healthy individuals. Using ultrasound, splenomegaly was found in 61.7% of H. pylori-infected subjects compared to only 8.7% noted in the group of H. pylori-non-infected individuals (P < 0.0001). Splenomegaly was also found in 47.8% of CIN patients compared to 12.8% in the group of non-CIN subjects (P = 0.0003). However, applying the two-way ANOVA test, a statistically significant effect on splenic volume was documented for "factor H. pylori " (F1(102) = 16.800, P < 0.0001) but not for "factor CIN" (F1(102) = 3.213, P = 0.0760), suggesting that CIN-associated splenomegaly is probably due to H. pylori infection.

Authors+Show Affiliations

Department of Hematology of the University of Crete School of Medicine, Heraklion, Crete, Greece. epapadak@med.uoc.grNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16432851

Citation

Papadaki, Helen A., et al. "Helicobacter Pylori Infection Is Probably the Cause of Chronic Idiopathic Neutropenia (CIN)-associated Splenomegaly." American Journal of Hematology, vol. 81, no. 2, 2006, pp. 142-4.
Papadaki HA, Pontikoglou C, Eliopoulos DG, et al. Helicobacter pylori infection is probably the cause of chronic idiopathic neutropenia (CIN)-associated splenomegaly. Am J Hematol. 2006;81(2):142-4.
Papadaki, H. A., Pontikoglou, C., Eliopoulos, D. G., Pyrovolaki, K., Spyridaki, R., & Eliopoulos, G. D. (2006). Helicobacter pylori infection is probably the cause of chronic idiopathic neutropenia (CIN)-associated splenomegaly. American Journal of Hematology, 81(2), pp. 142-4.
Papadaki HA, et al. Helicobacter Pylori Infection Is Probably the Cause of Chronic Idiopathic Neutropenia (CIN)-associated Splenomegaly. Am J Hematol. 2006;81(2):142-4. PubMed PMID: 16432851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Helicobacter pylori infection is probably the cause of chronic idiopathic neutropenia (CIN)-associated splenomegaly. AU - Papadaki,Helen A, AU - Pontikoglou,Charis, AU - Eliopoulos,Dimitris G, AU - Pyrovolaki,Katerina, AU - Spyridaki,Rania, AU - Eliopoulos,George D, PY - 2006/1/25/pubmed PY - 2006/4/15/medline PY - 2006/1/25/entrez SP - 142 EP - 4 JF - American journal of hematology JO - Am. J. Hematol. VL - 81 IS - 2 N2 - Splenic volume and Helicobacter pylori (H. pylori) infection were evaluated in 67 patients with chronic idiopathic neutropenia (CIN) and 39 healthy individuals. Using ultrasound, splenomegaly was found in 61.7% of H. pylori-infected subjects compared to only 8.7% noted in the group of H. pylori-non-infected individuals (P < 0.0001). Splenomegaly was also found in 47.8% of CIN patients compared to 12.8% in the group of non-CIN subjects (P = 0.0003). However, applying the two-way ANOVA test, a statistically significant effect on splenic volume was documented for "factor H. pylori " (F1(102) = 16.800, P < 0.0001) but not for "factor CIN" (F1(102) = 3.213, P = 0.0760), suggesting that CIN-associated splenomegaly is probably due to H. pylori infection. SN - 0361-8609 UR - https://www.unboundmedicine.com/medline/citation/16432851/Helicobacter_pylori_infection_is_probably_the_cause_of_chronic_idiopathic_neutropenia__CIN__associated_splenomegaly_ L2 - https://doi.org/10.1002/ajh.20496 DB - PRIME DP - Unbound Medicine ER -