Tags

Type your tag names separated by a space and hit enter

Lactation and risk of endometrial cancer in Japan: a case-control study.
Tohoku J Exp Med 2006; 208(2):109-15TJ

Abstract

The incidence of endometrial cancer is rapidly increasing in Japan. Although the risk factors in European populations have been well described, there are few epidemiologic studies regarding risk factors for endometrial cancer in Japanese women. This hospital-based case-control study among Japanese women was carried out from 1998 to 2000. The cases were selected from women with endometrial cancer (n =155), and the controls selected from women attending the university gynecological outpatient clinic for cervical cancer screening (n = 96). Subjects were interviewed to ascertain breast feeding practices, contraceptive usage, as well as potential risk factors for endometrial cancer. We observed a lower risk of endometrial cancer associated with oral contraceptive (OC) and a higher risk associated with higher body mass index (BMI), and older ages at first and last delivery. Gravidity reduced odds ratio (OR) for endometrial cancer to 0.34 (95% confidence interval [CI] 0.13-0.92). Compared with parous women who had never breastfed, the multivariate OR for women with a history of breastfeeding was 0.37 (95% CI, 0.17-0.82). Additionally, a greater lapse of time since breastfeeding increased OR for endometrial cancer by over three times. In conclusion, the present study has indicated that breastfeeding reduces the risk of endometrial cancer in Japanese women.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16434833

Citation

Okamura, Chikako, et al. "Lactation and Risk of Endometrial Cancer in Japan: a Case-control Study." The Tohoku Journal of Experimental Medicine, vol. 208, no. 2, 2006, pp. 109-15.
Okamura C, Tsubono Y, Ito K, et al. Lactation and risk of endometrial cancer in Japan: a case-control study. Tohoku J Exp Med. 2006;208(2):109-15.
Okamura, C., Tsubono, Y., Ito, K., Niikura, H., Takano, T., Nagase, S., ... Yaegashi, N. (2006). Lactation and risk of endometrial cancer in Japan: a case-control study. The Tohoku Journal of Experimental Medicine, 208(2), pp. 109-15.
Okamura C, et al. Lactation and Risk of Endometrial Cancer in Japan: a Case-control Study. Tohoku J Exp Med. 2006;208(2):109-15. PubMed PMID: 16434833.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lactation and risk of endometrial cancer in Japan: a case-control study. AU - Okamura,Chikako, AU - Tsubono,Yoshitaka, AU - Ito,Kiyoshi, AU - Niikura,Hitoshi, AU - Takano,Tadao, AU - Nagase,Satoru, AU - Yoshinaga,Kohsuke, AU - Terada,Yukihiro, AU - Murakami,Takashi, AU - Sato,Shinji, AU - Aoki,Daisuke, AU - Jobo,Toshiko, AU - Okamura,Kunihiro, AU - Yaegashi,Nobuo, PY - 2006/1/26/pubmed PY - 2006/5/11/medline PY - 2006/1/26/entrez SP - 109 EP - 15 JF - The Tohoku journal of experimental medicine JO - Tohoku J. Exp. Med. VL - 208 IS - 2 N2 - The incidence of endometrial cancer is rapidly increasing in Japan. Although the risk factors in European populations have been well described, there are few epidemiologic studies regarding risk factors for endometrial cancer in Japanese women. This hospital-based case-control study among Japanese women was carried out from 1998 to 2000. The cases were selected from women with endometrial cancer (n =155), and the controls selected from women attending the university gynecological outpatient clinic for cervical cancer screening (n = 96). Subjects were interviewed to ascertain breast feeding practices, contraceptive usage, as well as potential risk factors for endometrial cancer. We observed a lower risk of endometrial cancer associated with oral contraceptive (OC) and a higher risk associated with higher body mass index (BMI), and older ages at first and last delivery. Gravidity reduced odds ratio (OR) for endometrial cancer to 0.34 (95% confidence interval [CI] 0.13-0.92). Compared with parous women who had never breastfed, the multivariate OR for women with a history of breastfeeding was 0.37 (95% CI, 0.17-0.82). Additionally, a greater lapse of time since breastfeeding increased OR for endometrial cancer by over three times. In conclusion, the present study has indicated that breastfeeding reduces the risk of endometrial cancer in Japanese women. SN - 0040-8727 UR - https://www.unboundmedicine.com/medline/citation/16434833/Lactation_and_risk_of_endometrial_cancer_in_Japan:_a_case_control_study_ L2 - https://japanlinkcenter.org/JST.JSTAGE/tjem/208.109?lang=en&from=PubMed DB - PRIME DP - Unbound Medicine ER -