Tags

Type your tag names separated by a space and hit enter

A low fat diet rich in fruits and vegetables may reduce the risk of developing prostate cancer.
Asian Pac J Cancer Prev 2005 Oct-Dec; 6(4):490-6AP

Abstract

BACKGROUND

Diet has been implicated in prostate cancer risk and there is evidence of risk reduction with a healthy diet. The objective of this population-based case control study was to examine whether a low fat diet rich in fruits and vegetables can reduce the risk of developing prostate cancer in Mumbai, India.

METHODS

Included in this study were microscopically proved cases of prostate cancer diagnosed during 1998 to 2000 and registered by Bombay Population Based Cancer Registry (n=594). The controls were healthy men belonging to the resident general population of Mumbai, India. Two controls for each case matched by age and place of residence were selected as the comparison group. Data on oil/fat consumption, fruits and vegetable consumption and other probable confounding factors were obtained by structured face-to-face interview. After exclusions, 390 cases and 780 controls were available for final analysis and confounding was controlled by multiple logistic regression.

RESULTS

58.7% of the control group consumed more than 3 kg of fruits and vegetables per week compared to 52.1% of the case group. Controlling for age and probable confounding factors, a statistically significant protective effect for prostate cancer was observed for those who consumed fruits and vegetables 2 to 3 kg (OR 0.5, 95%CI 0.3-0.8) and more than 3 kg (OR 0.4, 95% CI 0.3-0.6) per week compared to those who consumed less than 2 kg per week. The linear trend for the protective effect was highly significant with increase in the consumption of fruits and vegetables (p = 0.001). Even though not statistically significant, oil/fat consumption showed an elevated risk (OR 1.7, 95%CI 0.9-3.3) for those who consumed more than 2 kg of oil/fat per month compared to those who consumed less than 1 kg.

CONCLUSION

The findings from this study support the hypothesis that a low fat diet rich in fruits and vegetables may reduce the risk of prostate cancer.

Authors+Show Affiliations

Bombay Population Based Cancer Registry, Indian Cancer Society, Parel Mumbai 400 012, India. lizzy_sunny@yahoo.com

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16435998

Citation

Sunny, Lizzy. "A Low Fat Diet Rich in Fruits and Vegetables May Reduce the Risk of Developing Prostate Cancer." Asian Pacific Journal of Cancer Prevention : APJCP, vol. 6, no. 4, 2005, pp. 490-6.
Sunny L. A low fat diet rich in fruits and vegetables may reduce the risk of developing prostate cancer. Asian Pac J Cancer Prev. 2005;6(4):490-6.
Sunny, L. (2005). A low fat diet rich in fruits and vegetables may reduce the risk of developing prostate cancer. Asian Pacific Journal of Cancer Prevention : APJCP, 6(4), pp. 490-6.
Sunny L. A Low Fat Diet Rich in Fruits and Vegetables May Reduce the Risk of Developing Prostate Cancer. Asian Pac J Cancer Prev. 2005;6(4):490-6. PubMed PMID: 16435998.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A low fat diet rich in fruits and vegetables may reduce the risk of developing prostate cancer. A1 - Sunny,Lizzy, PY - 2006/1/27/pubmed PY - 2006/5/19/medline PY - 2006/1/27/entrez SP - 490 EP - 6 JF - Asian Pacific journal of cancer prevention : APJCP JO - Asian Pac. J. Cancer Prev. VL - 6 IS - 4 N2 - BACKGROUND: Diet has been implicated in prostate cancer risk and there is evidence of risk reduction with a healthy diet. The objective of this population-based case control study was to examine whether a low fat diet rich in fruits and vegetables can reduce the risk of developing prostate cancer in Mumbai, India. METHODS: Included in this study were microscopically proved cases of prostate cancer diagnosed during 1998 to 2000 and registered by Bombay Population Based Cancer Registry (n=594). The controls were healthy men belonging to the resident general population of Mumbai, India. Two controls for each case matched by age and place of residence were selected as the comparison group. Data on oil/fat consumption, fruits and vegetable consumption and other probable confounding factors were obtained by structured face-to-face interview. After exclusions, 390 cases and 780 controls were available for final analysis and confounding was controlled by multiple logistic regression. RESULTS: 58.7% of the control group consumed more than 3 kg of fruits and vegetables per week compared to 52.1% of the case group. Controlling for age and probable confounding factors, a statistically significant protective effect for prostate cancer was observed for those who consumed fruits and vegetables 2 to 3 kg (OR 0.5, 95%CI 0.3-0.8) and more than 3 kg (OR 0.4, 95% CI 0.3-0.6) per week compared to those who consumed less than 2 kg per week. The linear trend for the protective effect was highly significant with increase in the consumption of fruits and vegetables (p = 0.001). Even though not statistically significant, oil/fat consumption showed an elevated risk (OR 1.7, 95%CI 0.9-3.3) for those who consumed more than 2 kg of oil/fat per month compared to those who consumed less than 1 kg. CONCLUSION: The findings from this study support the hypothesis that a low fat diet rich in fruits and vegetables may reduce the risk of prostate cancer. SN - 1513-7368 UR - https://www.unboundmedicine.com/medline/citation/16435998/A_low_fat_diet_rich_in_fruits_and_vegetables_may_reduce_the_risk_of_developing_prostate_cancer_ L2 - http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:16435998&key=2005.6.4.490 DB - PRIME DP - Unbound Medicine ER -