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Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid-base status.
Eur J Anaesthesiol 2006; 23(8):676-9EJ

Abstract

BACKGROUND AND OBJECTIVE

We evaluated the effect of two different preload solutions: (i) Ringer's lactate (compound sodium lactate intravenous infusion BP) and (ii) 0.9% sodium chloride solution on the neonatal acid-base status of the newborn infants. The two standard regimens were compared to detect a possible difference.

METHODS

A 2 L crystalloid fluid bolus was administered immediately before spinal anaesthesia for elective Caesarean section in two groups of 20 healthy parturients, while rigorously maintaining maternal normotension.

RESULTS

No significant differences in the Apgar scores at 1 and 5 min, or infant well-being were demonstrated in either of the two groups. The data show that umbilical artery PCO2 is lower in the Ringer's lactate group and that pH is insignificantly higher by 0.03.

CONCLUSIONS

The choice of Ringer's lactate or saline for fluid preload does not have any effect on neonatal well-being.

Authors+Show Affiliations

Assaf Harofeh Medical Center, Department of Anesthesiology, Zerifin, Israel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16438767

Citation

Chanimov, M, et al. "Fluid Preload Before Spinal Anaesthesia in Caesarean Section: the Effect On Neonatal Acid-base Status." European Journal of Anaesthesiology, vol. 23, no. 8, 2006, pp. 676-9.
Chanimov M, Gershfeld S, Cohen ML, et al. Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid-base status. Eur J Anaesthesiol. 2006;23(8):676-9.
Chanimov, M., Gershfeld, S., Cohen, M. L., Sherman, D., & Bahar, M. (2006). Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid-base status. European Journal of Anaesthesiology, 23(8), pp. 676-9.
Chanimov M, et al. Fluid Preload Before Spinal Anaesthesia in Caesarean Section: the Effect On Neonatal Acid-base Status. Eur J Anaesthesiol. 2006;23(8):676-9. PubMed PMID: 16438767.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid-base status. AU - Chanimov,M, AU - Gershfeld,S, AU - Cohen,M L, AU - Sherman,D, AU - Bahar,M, Y1 - 2006/01/27/ PY - 2005/06/14/accepted PY - 2006/1/28/pubmed PY - 2007/12/15/medline PY - 2006/1/28/entrez SP - 676 EP - 9 JF - European journal of anaesthesiology JO - Eur J Anaesthesiol VL - 23 IS - 8 N2 - BACKGROUND AND OBJECTIVE: We evaluated the effect of two different preload solutions: (i) Ringer's lactate (compound sodium lactate intravenous infusion BP) and (ii) 0.9% sodium chloride solution on the neonatal acid-base status of the newborn infants. The two standard regimens were compared to detect a possible difference. METHODS: A 2 L crystalloid fluid bolus was administered immediately before spinal anaesthesia for elective Caesarean section in two groups of 20 healthy parturients, while rigorously maintaining maternal normotension. RESULTS: No significant differences in the Apgar scores at 1 and 5 min, or infant well-being were demonstrated in either of the two groups. The data show that umbilical artery PCO2 is lower in the Ringer's lactate group and that pH is insignificantly higher by 0.03. CONCLUSIONS: The choice of Ringer's lactate or saline for fluid preload does not have any effect on neonatal well-being. SN - 0265-0215 UR - https://www.unboundmedicine.com/medline/citation/16438767/Fluid_preload_before_spinal_anaesthesia_in_Caesarean_section:_the_effect_on_neonatal_acid_base_status_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=16438767.ui DB - PRIME DP - Unbound Medicine ER -