Tags

Type your tag names separated by a space and hit enter

Tannins from barks of Pinus caribaea protect Escherichia coli cells against DNA damage induced by gamma-rays.
Fitoterapia. 2006 Feb; 77(2):116-20.F

Abstract

This work was aimed to evaluate genotoxicity and antigenotoxicity activity against gamma-rays of a tannin fraction obtained from barks of Pinus caribaea, as well as to elucidate the antigenotoxic mechanisms involved in radioprotection by using different approaches as pre-, co- and post-irradiation cell treatments with plant extract. The tannin fraction was not genotoxic to Escherichia coli cells in experiments using different exposure times. This extract was antigenotoxic against gamma-rays when the cells were pre- or co-treated with this extracts, but not during post-irradiation treatments, suggesting a possibly antigenotoxic action through free radical scavenging mechanisms. The results are discussed in relation to the chemopreventive and therapeutic potential of the studied plant species.

Authors+Show Affiliations

Fuentes JL
Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear (CEADEN), Miramar, Playa, Ciudad de la Habana, Cuba. jlfuentes2005@yahoo.es
Vernhe M
No affiliation info available
Cuetara EB
No affiliation info available
Sánchez-Lamar A
No affiliation info available
Santana JL
No affiliation info available
Llagostera M
No affiliation info available

MeSH

DNA DamageDNA, BacterialEscherichia coliGamma RaysMutagenicity TestsPinusPlant BarkPlant ExtractsRadiation-Protective AgentsTannins

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16439067

Citation

Fuentes, J L., et al. "Tannins From Barks of Pinus Caribaea Protect Escherichia Coli Cells Against DNA Damage Induced By Gamma-rays." Fitoterapia, vol. 77, no. 2, 2006, pp. 116-20.
Fuentes JL, Vernhe M, Cuetara EB, et al. Tannins from barks of Pinus caribaea protect Escherichia coli cells against DNA damage induced by gamma-rays. Fitoterapia. 2006;77(2):116-20.
Fuentes, J. L., Vernhe, M., Cuetara, E. B., Sánchez-Lamar, A., Santana, J. L., & Llagostera, M. (2006). Tannins from barks of Pinus caribaea protect Escherichia coli cells against DNA damage induced by gamma-rays. Fitoterapia, 77(2), 116-20.
Fuentes JL, et al. Tannins From Barks of Pinus Caribaea Protect Escherichia Coli Cells Against DNA Damage Induced By Gamma-rays. Fitoterapia. 2006;77(2):116-20. PubMed PMID: 16439067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tannins from barks of Pinus caribaea protect Escherichia coli cells against DNA damage induced by gamma-rays. AU - Fuentes,J L, AU - Vernhe,M, AU - Cuetara,E B, AU - Sánchez-Lamar,A, AU - Santana,J L, AU - Llagostera,M, Y1 - 2006/01/24/ PY - 2005/04/27/received PY - 2005/11/17/accepted PY - 2006/1/28/pubmed PY - 2006/5/4/medline PY - 2006/1/28/entrez SP - 116 EP - 20 JF - Fitoterapia JO - Fitoterapia VL - 77 IS - 2 N2 - This work was aimed to evaluate genotoxicity and antigenotoxicity activity against gamma-rays of a tannin fraction obtained from barks of Pinus caribaea, as well as to elucidate the antigenotoxic mechanisms involved in radioprotection by using different approaches as pre-, co- and post-irradiation cell treatments with plant extract. The tannin fraction was not genotoxic to Escherichia coli cells in experiments using different exposure times. This extract was antigenotoxic against gamma-rays when the cells were pre- or co-treated with this extracts, but not during post-irradiation treatments, suggesting a possibly antigenotoxic action through free radical scavenging mechanisms. The results are discussed in relation to the chemopreventive and therapeutic potential of the studied plant species. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/16439067/Tannins_from_barks_of_Pinus_caribaea_protect_Escherichia_coli_cells_against_DNA_damage_induced_by_gamma_rays_ DB - PRIME DP - Unbound Medicine ER -