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Survey of pertussis in patients with prolonged cough.
J Microbiol Immunol Infect. 2006 Feb; 39(1):54-8.JM

Abstract

BACKGROUND AND PURPOSE

Pertussis is an acute respiratory tract illness resulting from Bordetella pertussis. Widespread use of pertussis vaccine over the past 50 years has decreased the incidence of pertussis. The incidence of pertussis in adolescents and adults has increased in many areas of the world. This study aimed to evaluate the etiologic role of B. pertussis in patients with prolonged cough in Taiwan.

METHODS

Patients with cough lasting for more than 1 week were recruited. Nasopharyngeal swabs were taken for culture of B. pertussis and detection of nucleic acid of B. pertussis by polymerase chain reaction. Serum samples were collected in a subset of patients for assay of immunoglobulin G and immunoglobulin A antibodies against pertussis toxin.

RESULTS

In total, 111 patients were recruited. Thirty-three patients agreed to have their serum samples taken and tested. Eight patients had evidence of acute infection with B. pertussis; among them, 1 was diagnosed by polymerase chain reaction and 7 by serology. Older subjects were more likely to suffer from pertussis than younger subjects. The incidence of pertussis in patients with prolonged cough was 7.2%. However, the rate could have been as high as 21% in those with serum samples tested.

CONCLUSIONS

We conclude that pertussis is a prevalent disease in Taiwan, especially in adolescents and adults.

Authors+Show Affiliations

Department of Pediatrics, Taiwan Adventist Hospital, Taipei, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16440124

Citation

Hu, Jen Jan, et al. "Survey of Pertussis in Patients With Prolonged Cough." Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi, vol. 39, no. 1, 2006, pp. 54-8.
Hu JJ, Lu CY, Chang LY, et al. Survey of pertussis in patients with prolonged cough. J Microbiol Immunol Infect. 2006;39(1):54-8.
Hu, J. J., Lu, C. Y., Chang, L. Y., Huang, C. H., Chou, C. C., Huang, F. Y., Lee, C. Y., & Huang, L. M. (2006). Survey of pertussis in patients with prolonged cough. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi, 39(1), 54-8.
Hu JJ, et al. Survey of Pertussis in Patients With Prolonged Cough. J Microbiol Immunol Infect. 2006;39(1):54-8. PubMed PMID: 16440124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Survey of pertussis in patients with prolonged cough. AU - Hu,Jen Jan, AU - Lu,Chun Yi, AU - Chang,Luan Yin, AU - Huang,Chin Hao, AU - Chou,Chen Cheng, AU - Huang,Fu Yuan, AU - Lee,Chin Yun, AU - Huang,Li Min, PY - 2006/1/28/pubmed PY - 2006/3/31/medline PY - 2006/1/28/entrez SP - 54 EP - 8 JF - Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi JO - J Microbiol Immunol Infect VL - 39 IS - 1 N2 - BACKGROUND AND PURPOSE: Pertussis is an acute respiratory tract illness resulting from Bordetella pertussis. Widespread use of pertussis vaccine over the past 50 years has decreased the incidence of pertussis. The incidence of pertussis in adolescents and adults has increased in many areas of the world. This study aimed to evaluate the etiologic role of B. pertussis in patients with prolonged cough in Taiwan. METHODS: Patients with cough lasting for more than 1 week were recruited. Nasopharyngeal swabs were taken for culture of B. pertussis and detection of nucleic acid of B. pertussis by polymerase chain reaction. Serum samples were collected in a subset of patients for assay of immunoglobulin G and immunoglobulin A antibodies against pertussis toxin. RESULTS: In total, 111 patients were recruited. Thirty-three patients agreed to have their serum samples taken and tested. Eight patients had evidence of acute infection with B. pertussis; among them, 1 was diagnosed by polymerase chain reaction and 7 by serology. Older subjects were more likely to suffer from pertussis than younger subjects. The incidence of pertussis in patients with prolonged cough was 7.2%. However, the rate could have been as high as 21% in those with serum samples tested. CONCLUSIONS: We conclude that pertussis is a prevalent disease in Taiwan, especially in adolescents and adults. SN - 1684-1182 UR - https://www.unboundmedicine.com/medline/citation/16440124/Survey_of_pertussis_in_patients_with_prolonged_cough_ L2 - https://medlineplus.gov/cough.html DB - PRIME DP - Unbound Medicine ER -