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[Association of systemic lupus erythematosus and Sjögren's syndrome].
Orv Hetil. 2005 Dec 11; 146(50):2533-8.OH

Abstract

INTRODUCTION

Systemic lupus erythematosus and Sjögren's syndrome are multisystemic autoimmune diseases which can be associated to each other.

OBJECTIVE

To investigate if there are any distinct clinical, laboratory or serologic features due to the association of the two diseases that can influence the follow up of these patients.

PATIENTS AND METHODS

The authors proved the association of these two autoimmune diseases in 56 patients, and these patients' clinical, laboratory and immunoserologic alterations. 50 patients with Sjögren's syndrome and 50 patients with systemic lupus erythematosus were used as control groups.

RESULTS

Compared with Sjögren's syndrome alone, in the cases of the association of the diseases, rheumatoid factor was present less frequently, Ro/SS-A, La/SS-B and DNA antibodies were present more frequently, such as antiphospholipid autoantibodies and antiphospholipid syndrome. Anaemia, leukopenia and lymphopenia were detected more often and the patients were younger than in Sjögren's syndrome. Also, affection of the lung, kidney, skin, central nervous system and serous membranes are more common. The group with systemic lupus erythematosus differs in being older, having thyroiditis, Ro/SS-A, La/SS-B and DNA more frequently.

CONCLUSION

Definitive clinical, laboratory and serological features make the difference between the association of the two diseases and the diseases observed alone.

Authors+Show Affiliations

Debreceni Egyetem Orvos- es Egészségtudományi Centrum, Belgyógyászati Intézet.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

hun

PubMed ID

16440498

Citation

Szántó, Antónia, et al. "[Association of Systemic Lupus Erythematosus and Sjögren's Syndrome]." Orvosi Hetilap, vol. 146, no. 50, 2005, pp. 2533-8.
Szántó A, Kiss E, Sas A, et al. [Association of systemic lupus erythematosus and Sjögren's syndrome]. Orv Hetil. 2005;146(50):2533-8.
Szántó, A., Kiss, E., Sas, A., Szegedi, G., & Zeher, M. (2005). [Association of systemic lupus erythematosus and Sjögren's syndrome]. Orvosi Hetilap, 146(50), 2533-8.
Szántó A, et al. [Association of Systemic Lupus Erythematosus and Sjögren's Syndrome]. Orv Hetil. 2005 Dec 11;146(50):2533-8. PubMed PMID: 16440498.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Association of systemic lupus erythematosus and Sjögren's syndrome]. AU - Szántó,Antónia, AU - Kiss,Emese, AU - Sas,Attila, AU - Szegedi,Gyula, AU - Zeher,Margit, PY - 2006/1/31/pubmed PY - 2006/3/3/medline PY - 2006/1/31/entrez SP - 2533 EP - 8 JF - Orvosi hetilap JO - Orv Hetil VL - 146 IS - 50 N2 - INTRODUCTION: Systemic lupus erythematosus and Sjögren's syndrome are multisystemic autoimmune diseases which can be associated to each other. OBJECTIVE: To investigate if there are any distinct clinical, laboratory or serologic features due to the association of the two diseases that can influence the follow up of these patients. PATIENTS AND METHODS: The authors proved the association of these two autoimmune diseases in 56 patients, and these patients' clinical, laboratory and immunoserologic alterations. 50 patients with Sjögren's syndrome and 50 patients with systemic lupus erythematosus were used as control groups. RESULTS: Compared with Sjögren's syndrome alone, in the cases of the association of the diseases, rheumatoid factor was present less frequently, Ro/SS-A, La/SS-B and DNA antibodies were present more frequently, such as antiphospholipid autoantibodies and antiphospholipid syndrome. Anaemia, leukopenia and lymphopenia were detected more often and the patients were younger than in Sjögren's syndrome. Also, affection of the lung, kidney, skin, central nervous system and serous membranes are more common. The group with systemic lupus erythematosus differs in being older, having thyroiditis, Ro/SS-A, La/SS-B and DNA more frequently. CONCLUSION: Definitive clinical, laboratory and serological features make the difference between the association of the two diseases and the diseases observed alone. SN - 0030-6002 UR - https://www.unboundmedicine.com/medline/citation/16440498/[Association_of_systemic_lupus_erythematosus_and_Sjögren's_syndrome]_ L2 - http://www.diseaseinfosearch.org/result/9373 DB - PRIME DP - Unbound Medicine ER -