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[Polycystic ovary syndrome associated neoplasms].
Arq Bras Endocrinol Metabol 2005; 49(5):805-10AB

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women on reproductive age. PCOS is characterized by the presence of anovulation, infertility and hyperandrogenism and is associated with obesity and insulin resistance. A major risk for neoplasms of the reproductive tract, like endometrial, breast and ovary cancer seems to be related to PCOS. While several studies have shown an increased risk for endometrial hyperplasia and cancer in PCOS patients, the variability of the selection criteria for PCOS has been recognized as a potential bias for these data. PCOS women also present clinical characteristics that are related to risk factors for breast cancer and some epidemiological evidences have been described on this issue. However, until now, a clear association between the presence of PCOS and breast carcinoma has yet not been found. Finally, high local steroid and growth factor concentrations are considered risk factors for ovary carcinoma, and are frequently observed in PCOS women. In turn, few studies have addressed the possibility of a link between PCOS and ovarian cancer and the results are conflicting but suggest that this association is unlikely.

Authors+Show Affiliations

Serviço de Endocrinologia, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS. spritzer@ufrgs.br

Pub Type(s)

English Abstract
Journal Article
Review

Language

por

PubMed ID

16444364

Citation

Spritzer, Poli Mara, et al. "[Polycystic Ovary Syndrome Associated Neoplasms]." Arquivos Brasileiros De Endocrinologia E Metabologia, vol. 49, no. 5, 2005, pp. 805-10.
Spritzer PM, Morsch DM, Wiltgen D. [Polycystic ovary syndrome associated neoplasms]. Arq Bras Endocrinol Metabol. 2005;49(5):805-10.
Spritzer, P. M., Morsch, D. M., & Wiltgen, D. (2005). [Polycystic ovary syndrome associated neoplasms]. Arquivos Brasileiros De Endocrinologia E Metabologia, 49(5), pp. 805-10.
Spritzer PM, Morsch DM, Wiltgen D. [Polycystic Ovary Syndrome Associated Neoplasms]. Arq Bras Endocrinol Metabol. 2005;49(5):805-10. PubMed PMID: 16444364.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Polycystic ovary syndrome associated neoplasms]. AU - Spritzer,Poli Mara, AU - Morsch,Débora Martinho, AU - Wiltgen,Denusa, Y1 - 2006/01/23/ PY - 2006/1/31/pubmed PY - 2006/10/25/medline PY - 2006/1/31/entrez SP - 805 EP - 10 JF - Arquivos brasileiros de endocrinologia e metabologia JO - Arq Bras Endocrinol Metabol VL - 49 IS - 5 N2 - Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women on reproductive age. PCOS is characterized by the presence of anovulation, infertility and hyperandrogenism and is associated with obesity and insulin resistance. A major risk for neoplasms of the reproductive tract, like endometrial, breast and ovary cancer seems to be related to PCOS. While several studies have shown an increased risk for endometrial hyperplasia and cancer in PCOS patients, the variability of the selection criteria for PCOS has been recognized as a potential bias for these data. PCOS women also present clinical characteristics that are related to risk factors for breast cancer and some epidemiological evidences have been described on this issue. However, until now, a clear association between the presence of PCOS and breast carcinoma has yet not been found. Finally, high local steroid and growth factor concentrations are considered risk factors for ovary carcinoma, and are frequently observed in PCOS women. In turn, few studies have addressed the possibility of a link between PCOS and ovarian cancer and the results are conflicting but suggest that this association is unlikely. SN - 0004-2730 UR - https://www.unboundmedicine.com/medline/citation/16444364/[Polycystic_ovary_syndrome_associated_neoplasms]_ L2 - https://medlineplus.gov/ovariancancer.html DB - PRIME DP - Unbound Medicine ER -