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Discovery of a pituitary adenoma following treatment with a gonadotropin-releasing hormone agonist in a patient with prostate cancer.
Int J Urol. 2006 Jan; 13(1):87-8.IJ

Abstract

We report the case of a T3 prostate cancer in a 70-year-old white man. Hormone therapy represents a prominent branch in the treatment of locally advanced and metastatic prostate cancer. Gonadotropin-releasing hormone agonists have been proven to have a double effect on androgen metabolism: an initially stimulating, followed by an inhibitory, effect on the pituitary gland. This phenomenon may be noxious in the case of gonadotroph adenoma, with subsequent symptoms of intracranial hypertension. Gonadotropin-releasing hormone antagonists (abarelix), by avoiding the flare-up reaction, might be used in such instances.

Authors+Show Affiliations

Massoud W
Department of Urology, Lyon-Sud Hospital, Lyon, France.
Paparel P
No affiliation info available
Lopez JG
No affiliation info available
Perrin P
No affiliation info available
Daumont M
No affiliation info available
Ruffion A
No affiliation info available

MeSH

AdenocarcinomaAdenomaAgedAntineoplastic Agents, HormonalBiopsyDiagnosis, DifferentialGonadotropin-Releasing HormoneHumansLeuprolideMagnetic Resonance ImagingMalePituitary NeoplasmsProstatic NeoplasmsTomography, X-Ray Computed

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16448441

Citation

Massoud, Walid, et al. "Discovery of a Pituitary Adenoma Following Treatment With a Gonadotropin-releasing Hormone Agonist in a Patient With Prostate Cancer." International Journal of Urology : Official Journal of the Japanese Urological Association, vol. 13, no. 1, 2006, pp. 87-8.
Massoud W, Paparel P, Lopez JG, et al. Discovery of a pituitary adenoma following treatment with a gonadotropin-releasing hormone agonist in a patient with prostate cancer. Int J Urol. 2006;13(1):87-8.
Massoud, W., Paparel, P., Lopez, J. G., Perrin, P., Daumont, M., & Ruffion, A. (2006). Discovery of a pituitary adenoma following treatment with a gonadotropin-releasing hormone agonist in a patient with prostate cancer. International Journal of Urology : Official Journal of the Japanese Urological Association, 13(1), 87-8.
Massoud W, et al. Discovery of a Pituitary Adenoma Following Treatment With a Gonadotropin-releasing Hormone Agonist in a Patient With Prostate Cancer. Int J Urol. 2006;13(1):87-8. PubMed PMID: 16448441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Discovery of a pituitary adenoma following treatment with a gonadotropin-releasing hormone agonist in a patient with prostate cancer. AU - Massoud,Walid, AU - Paparel,Philippe, AU - Lopez,Jean-Gabriel, AU - Perrin,Paul, AU - Daumont,Michele, AU - Ruffion,Alain, PY - 2006/2/2/pubmed PY - 2006/6/14/medline PY - 2006/2/2/entrez SP - 87 EP - 8 JF - International journal of urology : official journal of the Japanese Urological Association JO - Int J Urol VL - 13 IS - 1 N2 - We report the case of a T3 prostate cancer in a 70-year-old white man. Hormone therapy represents a prominent branch in the treatment of locally advanced and metastatic prostate cancer. Gonadotropin-releasing hormone agonists have been proven to have a double effect on androgen metabolism: an initially stimulating, followed by an inhibitory, effect on the pituitary gland. This phenomenon may be noxious in the case of gonadotroph adenoma, with subsequent symptoms of intracranial hypertension. Gonadotropin-releasing hormone antagonists (abarelix), by avoiding the flare-up reaction, might be used in such instances. SN - 0919-8172 UR - https://www.unboundmedicine.com/medline/citation/16448441/Discovery_of_a_pituitary_adenoma_following_treatment_with_a_gonadotropin_releasing_hormone_agonist_in_a_patient_with_prostate_cancer_ DB - PRIME DP - Unbound Medicine ER -