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Prevalence of hepatitis B among Afghan refugees living in Balochistan, Pakistan.
Int J Infect Dis 2006; 10(3):242-7IJ

Abstract

OBJECTIVE

Continued civil war and political instability in Afghanistan have lead to a huge influx of refugees into the neighboring provinces in Pakistan. This study was conducted to estimate seroprevalence of hepatitis B and to identify potential risk factors for hepatitis B virus (HBV) transmission among the refugees living in the camps of Balochistan Province, Pakistan.

METHODS

A cross-sectional survey of hepatitis B surface antigen (HBsAg) was conducted during October 2003. We obtained the registration list to select families randomly from the refugee camps. A husband, wife and one of their children, selected at random, were enrolled in the study. Study subjects with positive laboratory results for HBsAg were compared with those who were negative for HBsAg.

RESULTS

Field workers interviewed 301 families with a total of 903 study subjects. Blood specimens of 75 study subjects (8.3%, 95% CI 6.6-10.3) were positive for HBsAg. There were 37 husbands (12.3%, 95% CI 7.2-14.4) and 21 wives (7.0%, 95% CI 4.5-10.6) positive for HBsAg. Out of 301 children, 17 (5.6%, 95% CI 3.4-9.1) were positive for HBsAg. Receiving more than ten injections during the previous year increased the risk of HBV infection (OR 3.5, 95% CI 1.8-6.7). A child positive for HBsAg was more likely to have a positive parent compared to an HBsAg negative child (OR 5.7, 95% CI 2.0-16.5).

CONCLUSION

Hepatitis B is highly endemic among Afghan refugees living in these camps. Unsafe injection practices will continue to cause a steady increase in the magnitude of this health problem until appropriate control measures are taken. The possibility of mother-to-child transmission underscores the need to include vaccination against hepatitis B as part of routine immunization in this population.

Authors+Show Affiliations

WHO, Polio Eradication Initiative, Kandahar, Afghanistan. arshadwho@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16448838

Citation

Quddus, Arshad, et al. "Prevalence of Hepatitis B Among Afghan Refugees Living in Balochistan, Pakistan." International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, vol. 10, no. 3, 2006, pp. 242-7.
Quddus A, Luby SP, Jamal Z, et al. Prevalence of hepatitis B among Afghan refugees living in Balochistan, Pakistan. Int J Infect Dis. 2006;10(3):242-7.
Quddus, A., Luby, S. P., Jamal, Z., & Jafar, T. (2006). Prevalence of hepatitis B among Afghan refugees living in Balochistan, Pakistan. International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 10(3), pp. 242-7.
Quddus A, et al. Prevalence of Hepatitis B Among Afghan Refugees Living in Balochistan, Pakistan. Int J Infect Dis. 2006;10(3):242-7. PubMed PMID: 16448838.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of hepatitis B among Afghan refugees living in Balochistan, Pakistan. AU - Quddus,Arshad, AU - Luby,Stephen P, AU - Jamal,Zahid, AU - Jafar,Tariq, Y1 - 2006/01/31/ PY - 2005/01/17/received PY - 2005/04/18/revised PY - 2005/04/26/accepted PY - 2006/2/2/pubmed PY - 2006/6/28/medline PY - 2006/2/2/entrez SP - 242 EP - 7 JF - International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases JO - Int. J. Infect. Dis. VL - 10 IS - 3 N2 - OBJECTIVE: Continued civil war and political instability in Afghanistan have lead to a huge influx of refugees into the neighboring provinces in Pakistan. This study was conducted to estimate seroprevalence of hepatitis B and to identify potential risk factors for hepatitis B virus (HBV) transmission among the refugees living in the camps of Balochistan Province, Pakistan. METHODS: A cross-sectional survey of hepatitis B surface antigen (HBsAg) was conducted during October 2003. We obtained the registration list to select families randomly from the refugee camps. A husband, wife and one of their children, selected at random, were enrolled in the study. Study subjects with positive laboratory results for HBsAg were compared with those who were negative for HBsAg. RESULTS: Field workers interviewed 301 families with a total of 903 study subjects. Blood specimens of 75 study subjects (8.3%, 95% CI 6.6-10.3) were positive for HBsAg. There were 37 husbands (12.3%, 95% CI 7.2-14.4) and 21 wives (7.0%, 95% CI 4.5-10.6) positive for HBsAg. Out of 301 children, 17 (5.6%, 95% CI 3.4-9.1) were positive for HBsAg. Receiving more than ten injections during the previous year increased the risk of HBV infection (OR 3.5, 95% CI 1.8-6.7). A child positive for HBsAg was more likely to have a positive parent compared to an HBsAg negative child (OR 5.7, 95% CI 2.0-16.5). CONCLUSION: Hepatitis B is highly endemic among Afghan refugees living in these camps. Unsafe injection practices will continue to cause a steady increase in the magnitude of this health problem until appropriate control measures are taken. The possibility of mother-to-child transmission underscores the need to include vaccination against hepatitis B as part of routine immunization in this population. SN - 1201-9712 UR - https://www.unboundmedicine.com/medline/citation/16448838/Prevalence_of_hepatitis_B_among_Afghan_refugees_living_in_Balochistan_Pakistan_ L2 - http://linkinghub.elsevier.com/retrieve/pii/S1201-9712(05)00169-4 DB - PRIME DP - Unbound Medicine ER -