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[Management of cutaneous leishmaniasis in adults and children].
Med Trop (Mars). 2005 Nov; 65(5):487-95.MT

Abstract

Cutaneous leishmaniasis can present a variety of clinical features and courses. The causative Leishmania species is an important prognostic factor in immunocompetent patients. Local treatment modalities including topical paromomycin, cryotherapy, localized controlled heat, carbon dioxide laser therapy, or intralesional meglumine antimoniate can be effective against Leishmania major or Leishmania tropica. Oral fluconazole may be a second-line treatment. Parenteral antimonials are useful for persistent or recurrent Old World leishmaniasis. For New World leishmaniasis, parenteral antimonials represent the first-line treatment in all forms except those caused by Leishmania guyanensis in which pentamidine is preferable. Liposomal amphotericin B appears to be effective for treatment of cutaneous leishmaniasis but further study will be needed. Results using oral Miltefosine are promising against Indian kala-azar (Leishmania donovani) but disappointing against South American leishmaniasis.

Authors+Show Affiliations

Unite des urgences pédiatriques, CHU Nord, Chemin des Bourrely, 13915 Marseille, France. philippe.minodier@ap-hm.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

16465821

Citation

Minodier, P, et al. "[Management of Cutaneous Leishmaniasis in Adults and Children]." Medecine Tropicale : Revue Du Corps De Sante Colonial, vol. 65, no. 5, 2005, pp. 487-95.
Minodier P, Noël G, Blanc P, et al. [Management of cutaneous leishmaniasis in adults and children]. Med Trop (Mars). 2005;65(5):487-95.
Minodier, P., Noël, G., Blanc, P., Uters, M., Retornaz, K., & Garnier, J. M. (2005). [Management of cutaneous leishmaniasis in adults and children]. Medecine Tropicale : Revue Du Corps De Sante Colonial, 65(5), 487-95.
Minodier P, et al. [Management of Cutaneous Leishmaniasis in Adults and Children]. Med Trop (Mars). 2005;65(5):487-95. PubMed PMID: 16465821.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Management of cutaneous leishmaniasis in adults and children]. AU - Minodier,P, AU - Noël,G, AU - Blanc,P, AU - Uters,M, AU - Retornaz,K, AU - Garnier,J M, PY - 2006/2/10/pubmed PY - 2006/3/1/medline PY - 2006/2/10/entrez SP - 487 EP - 95 JF - Medecine tropicale : revue du Corps de sante colonial JO - Med Trop (Mars) VL - 65 IS - 5 N2 - Cutaneous leishmaniasis can present a variety of clinical features and courses. The causative Leishmania species is an important prognostic factor in immunocompetent patients. Local treatment modalities including topical paromomycin, cryotherapy, localized controlled heat, carbon dioxide laser therapy, or intralesional meglumine antimoniate can be effective against Leishmania major or Leishmania tropica. Oral fluconazole may be a second-line treatment. Parenteral antimonials are useful for persistent or recurrent Old World leishmaniasis. For New World leishmaniasis, parenteral antimonials represent the first-line treatment in all forms except those caused by Leishmania guyanensis in which pentamidine is preferable. Liposomal amphotericin B appears to be effective for treatment of cutaneous leishmaniasis but further study will be needed. Results using oral Miltefosine are promising against Indian kala-azar (Leishmania donovani) but disappointing against South American leishmaniasis. SN - 0025-682X UR - https://www.unboundmedicine.com/medline/citation/16465821/[Management_of_cutaneous_leishmaniasis_in_adults_and_children]_ L2 - http://www.diseaseinfosearch.org/result/4166 DB - PRIME DP - Unbound Medicine ER -