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Significance of papillary lesions at percutaneous breast biopsy.
Ann Surg Oncol. 2006 Apr; 13(4):480-2.AS

Abstract

BACKGROUND

The management of nonpalpable papillary lesions found in specimens obtained by percutaneous breast biopsy is controversial. We reviewed the treatment of patients found to have papillary lesions by stereotactic, sonographic, or fine-needle aspiration breast biopsy to identify indications for surgical excision.

METHODS

Consecutive patients with intraductal papilloma, atypical papilloma/papilloma with atypical ductal hyperplasia, papillary neoplasm, and papillomatosis according to percutaneous breast biopsy were identified from radiology records. The charts were reviewed to identify patients who had subsequent surgical excision, and the pathologic findings were correlated with the biopsy method and indications for surgery.

RESULTS

Papillary lesions were found in 120 biopsy samples from 109 patients. Malignancy was found at operation in 19 (24%) of 80 lesions that underwent surgical excision: 12 (63%) were ductal carcinoma-in-situ, 4 (21%) were infiltrating ductal carcinoma, 2 (11%) were infiltrating papillary carcinoma, and 1 (5%) was intracystic papillary carcinoma. Malignancy was found in 9 (30%) of 30 fine-needle biopsy papillary lesions, 6 (35%) of 17 core biopsy papillary lesions, and 4 (12%) of 33 stereotactic biopsy papillary lesions. Malignancy was missed significantly less frequently with stereotactic biopsy (P<.05).

CONCLUSIONS

Malignancy is frequently found at surgical excision for papillary lesions found on percutaneous breast biopsy. Malignancy is missed significantly less frequently with stereotactic biopsy.

Authors+Show Affiliations

Valdes EK
Department of Surgery, Comprehensive Breast Service, St. Luke's Roosevelt Medical Center, 425 West 59th Street Suite 7A, New York, New York 10019, USA. edvaldes@chpnet.org
Tartter PI
No affiliation info available
Genelus-Dominique E
No affiliation info available
Guilbaud DA
No affiliation info available
Rosenbaum-Smith S
No affiliation info available
Estabrook A
No affiliation info available

MeSH

Biopsy, NeedleBreastBreast NeoplasmsCarcinoma in SituCarcinoma, Ductal, BreastCarcinoma, PapillaryDiagnosis, DifferentialFemaleHumansHyperplasiaPapillomaPapilloma, IntraductalUltrasonography, Mammary

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16474908

Citation

Valdes, Edna K., et al. "Significance of Papillary Lesions at Percutaneous Breast Biopsy." Annals of Surgical Oncology, vol. 13, no. 4, 2006, pp. 480-2.
Valdes EK, Tartter PI, Genelus-Dominique E, et al. Significance of papillary lesions at percutaneous breast biopsy. Ann Surg Oncol. 2006;13(4):480-2.
Valdes, E. K., Tartter, P. I., Genelus-Dominique, E., Guilbaud, D. A., Rosenbaum-Smith, S., & Estabrook, A. (2006). Significance of papillary lesions at percutaneous breast biopsy. Annals of Surgical Oncology, 13(4), 480-2.
Valdes EK, et al. Significance of Papillary Lesions at Percutaneous Breast Biopsy. Ann Surg Oncol. 2006;13(4):480-2. PubMed PMID: 16474908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Significance of papillary lesions at percutaneous breast biopsy. AU - Valdes,Edna K, AU - Tartter,Paul I, AU - Genelus-Dominique,Elvita, AU - Guilbaud,Deborah-Alexis, AU - Rosenbaum-Smith,Sharon, AU - Estabrook,Alison, Y1 - 2006/02/14/ PY - 2005/08/01/received PY - 2005/10/18/accepted PY - 2006/2/14/pubmed PY - 2006/9/23/medline PY - 2006/2/14/entrez SP - 480 EP - 2 JF - Annals of surgical oncology JO - Ann Surg Oncol VL - 13 IS - 4 N2 - BACKGROUND: The management of nonpalpable papillary lesions found in specimens obtained by percutaneous breast biopsy is controversial. We reviewed the treatment of patients found to have papillary lesions by stereotactic, sonographic, or fine-needle aspiration breast biopsy to identify indications for surgical excision. METHODS: Consecutive patients with intraductal papilloma, atypical papilloma/papilloma with atypical ductal hyperplasia, papillary neoplasm, and papillomatosis according to percutaneous breast biopsy were identified from radiology records. The charts were reviewed to identify patients who had subsequent surgical excision, and the pathologic findings were correlated with the biopsy method and indications for surgery. RESULTS: Papillary lesions were found in 120 biopsy samples from 109 patients. Malignancy was found at operation in 19 (24%) of 80 lesions that underwent surgical excision: 12 (63%) were ductal carcinoma-in-situ, 4 (21%) were infiltrating ductal carcinoma, 2 (11%) were infiltrating papillary carcinoma, and 1 (5%) was intracystic papillary carcinoma. Malignancy was found in 9 (30%) of 30 fine-needle biopsy papillary lesions, 6 (35%) of 17 core biopsy papillary lesions, and 4 (12%) of 33 stereotactic biopsy papillary lesions. Malignancy was missed significantly less frequently with stereotactic biopsy (P<.05). CONCLUSIONS: Malignancy is frequently found at surgical excision for papillary lesions found on percutaneous breast biopsy. Malignancy is missed significantly less frequently with stereotactic biopsy. SN - 1068-9265 UR - https://www.unboundmedicine.com/medline/citation/16474908/Significance_of_papillary_lesions_at_percutaneous_breast_biopsy_ DB - PRIME DP - Unbound Medicine ER -