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A comparison of the insertion characteristics of the laryngeal tube and the laryngeal mask airway: a study of the ED50 propofol requirements.
Anaesthesia. 2006 Mar; 61(3):229-33.A

Abstract

The purpose of this prospective randomised double-blind study was to determine the effective dose of propofol required for the successful first attempt insertion of the laryngeal tube compared with the laryngeal mask airway in patients co-induced using alfentanil 5 microg.kg(-1), undergoing short elective gynaecological procedures. The first patient in each group received propofol 2.5 mg.kg(-1) for induction. In accordance with Dixon's up-and-down method, the dose of propofol for consecutive patients in each group was varied with increments or decrements of 0.5 mg.kg(-1) based on the previous patient 'all-or-none' purposeful movement response to first attempt of insertion of the randomised device. The ED50 (SD) of propofol was 2.66 (0.86) mg.kg(-1) and 2.33 (0.37) mg.kg(-1) for the laryngeal tube and laryngeal mask patients, respectively, which did not reach statistical significance (p = 0.40). We conclude therefore that the insertion of the two airway devices requires similar bolus doses of propofol when alfentanil is used as the co-induction drug.

Authors+Show Affiliations

Department of Anaesthesia, Coombe Women Hospital, Dublin, Ireland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16480346

Citation

Burlacu, C L., et al. "A Comparison of the Insertion Characteristics of the Laryngeal Tube and the Laryngeal Mask Airway: a Study of the ED50 Propofol Requirements." Anaesthesia, vol. 61, no. 3, 2006, pp. 229-33.
Burlacu CL, Gaskin P, Fernandes A, et al. A comparison of the insertion characteristics of the laryngeal tube and the laryngeal mask airway: a study of the ED50 propofol requirements. Anaesthesia. 2006;61(3):229-33.
Burlacu, C. L., Gaskin, P., Fernandes, A., Carey, M., & Briggs, L. (2006). A comparison of the insertion characteristics of the laryngeal tube and the laryngeal mask airway: a study of the ED50 propofol requirements. Anaesthesia, 61(3), 229-33.
Burlacu CL, et al. A Comparison of the Insertion Characteristics of the Laryngeal Tube and the Laryngeal Mask Airway: a Study of the ED50 Propofol Requirements. Anaesthesia. 2006;61(3):229-33. PubMed PMID: 16480346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of the insertion characteristics of the laryngeal tube and the laryngeal mask airway: a study of the ED50 propofol requirements. AU - Burlacu,C L, AU - Gaskin,P, AU - Fernandes,A, AU - Carey,M, AU - Briggs,L, PY - 2006/2/17/pubmed PY - 2006/3/24/medline PY - 2006/2/17/entrez SP - 229 EP - 33 JF - Anaesthesia JO - Anaesthesia VL - 61 IS - 3 N2 - The purpose of this prospective randomised double-blind study was to determine the effective dose of propofol required for the successful first attempt insertion of the laryngeal tube compared with the laryngeal mask airway in patients co-induced using alfentanil 5 microg.kg(-1), undergoing short elective gynaecological procedures. The first patient in each group received propofol 2.5 mg.kg(-1) for induction. In accordance with Dixon's up-and-down method, the dose of propofol for consecutive patients in each group was varied with increments or decrements of 0.5 mg.kg(-1) based on the previous patient 'all-or-none' purposeful movement response to first attempt of insertion of the randomised device. The ED50 (SD) of propofol was 2.66 (0.86) mg.kg(-1) and 2.33 (0.37) mg.kg(-1) for the laryngeal tube and laryngeal mask patients, respectively, which did not reach statistical significance (p = 0.40). We conclude therefore that the insertion of the two airway devices requires similar bolus doses of propofol when alfentanil is used as the co-induction drug. SN - 0003-2409 UR - https://www.unboundmedicine.com/medline/citation/16480346/A_comparison_of_the_insertion_characteristics_of_the_laryngeal_tube_and_the_laryngeal_mask_airway:_a_study_of_the_ED50_propofol_requirements_ L2 - https://doi.org/10.1111/j.1365-2044.2005.04442.x DB - PRIME DP - Unbound Medicine ER -