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Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms.
Aliment Pharmacol Ther 2006; 23(5):607-16AP

Abstract

BACKGROUND

Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms.

AIM

To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms.

METHODS

Population-based postal survey carried out in France in 2003 among a representative sample of 8000 subjects.

RESULTS

The prevalence of frequent and occasional gastro-oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro-oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton-pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro-oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton-pump inhibitors.

CONCLUSIONS

This survey suggests that subjects complaining of frequent or occasional gastro-oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health-related quality of life and sought health care.

Authors+Show Affiliations

Service des Maladies de l'Appareil Digestif, Hôpital Pontchaillou, Rennes, France. jean-francois.bretagne@chu-rennes.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16480400

Citation

Bretagne, J F., et al. "Comparative Study of Characteristics and Disease Management Between Subjects With Frequent and Occasional Gastro-oesophageal Reflux Symptoms." Alimentary Pharmacology & Therapeutics, vol. 23, no. 5, 2006, pp. 607-16.
Bretagne JF, Honnorat C, Richard-Molard B, et al. Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. Aliment Pharmacol Ther. 2006;23(5):607-16.
Bretagne, J. F., Honnorat, C., Richard-Molard, B., Caekaert, A., & Barthélemy, P. (2006). Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. Alimentary Pharmacology & Therapeutics, 23(5), pp. 607-16.
Bretagne JF, et al. Comparative Study of Characteristics and Disease Management Between Subjects With Frequent and Occasional Gastro-oesophageal Reflux Symptoms. Aliment Pharmacol Ther. 2006 Mar 1;23(5):607-16. PubMed PMID: 16480400.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. AU - Bretagne,J F, AU - Honnorat,C, AU - Richard-Molard,B, AU - Caekaert,A, AU - Barthélemy,P, PY - 2006/2/17/pubmed PY - 2006/6/30/medline PY - 2006/2/17/entrez SP - 607 EP - 16 JF - Alimentary pharmacology & therapeutics JO - Aliment. Pharmacol. Ther. VL - 23 IS - 5 N2 - BACKGROUND: Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms. AIM: To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms. METHODS: Population-based postal survey carried out in France in 2003 among a representative sample of 8000 subjects. RESULTS: The prevalence of frequent and occasional gastro-oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro-oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton-pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro-oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton-pump inhibitors. CONCLUSIONS: This survey suggests that subjects complaining of frequent or occasional gastro-oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health-related quality of life and sought health care. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/16480400/Comparative_study_of_characteristics_and_disease_management_between_subjects_with_frequent_and_occasional_gastro_oesophageal_reflux_symptoms_ L2 - https://doi.org/10.1111/j.1365-2036.2006.02811.x DB - PRIME DP - Unbound Medicine ER -