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Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms.

Abstract

BACKGROUND

Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms.

AIM

To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms.

METHODS

Population-based postal survey carried out in France in 2003 among a representative sample of 8000 subjects.

RESULTS

The prevalence of frequent and occasional gastro-oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro-oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton-pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro-oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton-pump inhibitors.

CONCLUSIONS

This survey suggests that subjects complaining of frequent or occasional gastro-oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health-related quality of life and sought health care.

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  • Authors+Show Affiliations

    ,

    Service des Maladies de l'Appareil Digestif, Hôpital Pontchaillou, Rennes, France. jean-francois.bretagne@chu-rennes.fr

    , , ,

    Source

    Alimentary pharmacology & therapeutics 23:5 2006 Mar 01 pg 607-16

    MeSH

    Activities of Daily Living
    Adult
    Age Factors
    Alginates
    Antacids
    Drug Administration Schedule
    Drug Therapy, Combination
    Female
    France
    Gastroesophageal Reflux
    Humans
    Male
    Middle Aged
    Patient Acceptance of Health Care
    Patient Satisfaction
    Population Surveillance
    Prevalence
    Proton Pump Inhibitors
    Risk Factors
    Severity of Illness Index
    Time Factors

    Pub Type(s)

    Comparative Study
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    16480400

    Citation

    Bretagne, J F., et al. "Comparative Study of Characteristics and Disease Management Between Subjects With Frequent and Occasional Gastro-oesophageal Reflux Symptoms." Alimentary Pharmacology & Therapeutics, vol. 23, no. 5, 2006, pp. 607-16.
    Bretagne JF, Honnorat C, Richard-Molard B, et al. Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. Aliment Pharmacol Ther. 2006;23(5):607-16.
    Bretagne, J. F., Honnorat, C., Richard-Molard, B., Caekaert, A., & Barthélemy, P. (2006). Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. Alimentary Pharmacology & Therapeutics, 23(5), pp. 607-16.
    Bretagne JF, et al. Comparative Study of Characteristics and Disease Management Between Subjects With Frequent and Occasional Gastro-oesophageal Reflux Symptoms. Aliment Pharmacol Ther. 2006 Mar 1;23(5):607-16. PubMed PMID: 16480400.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Comparative study of characteristics and disease management between subjects with frequent and occasional gastro-oesophageal reflux symptoms. AU - Bretagne,J F, AU - Honnorat,C, AU - Richard-Molard,B, AU - Caekaert,A, AU - Barthélemy,P, PY - 2006/2/17/pubmed PY - 2006/6/30/medline PY - 2006/2/17/entrez SP - 607 EP - 16 JF - Alimentary pharmacology & therapeutics JO - Aliment. Pharmacol. Ther. VL - 23 IS - 5 N2 - BACKGROUND: Little is known about the distinctive characteristics of subjects with frequent (at least weekly) and occasional gastro-oesophageal reflux symptoms. AIM: To compare the characteristics and disease management of subjects complaining of at least weekly and less frequent gastro-oesophageal reflux symptoms. METHODS: Population-based postal survey carried out in France in 2003 among a representative sample of 8000 subjects. RESULTS: The prevalence of frequent and occasional gastro-oesophageal reflux symptoms was 7.8% and 23.4%, respectively. Compared to subjects with occasional gastro-oesophageal reflux symptoms, those with frequent symptoms were older, suffered from more severe symptoms and felt greater impact on daily living, despite a slightly shorter duration of symptoms. These subjects more often sought medical advice. Most of them had treated the last episode of symptoms primarily with a proton-pump inhibitor and less often with antacids/alginates. The degree of treatment satisfaction was lower in subjects with frequent gastro-oesophageal reflux symptoms, in relation to a more frequently observed persistence of symptoms irrespective of the medication used except for proton-pump inhibitors. CONCLUSIONS: This survey suggests that subjects complaining of frequent or occasional gastro-oesophageal reflux symptoms constitute two distinctive groups. Despite greater healthcare use, the former group shows a lower level of satisfaction with disease management. Nevertheless, a substantial subset of subjects with occasional symptoms also complained of impaired health-related quality of life and sought health care. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/16480400/Comparative_study_of_characteristics_and_disease_management_between_subjects_with_frequent_and_occasional_gastro_oesophageal_reflux_symptoms_ L2 - https://doi.org/10.1111/j.1365-2036.2006.02811.x DB - PRIME DP - Unbound Medicine ER -