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Viral load distribution in SARS outbreak.
Emerg Infect Dis. 2005 Dec; 11(12):1882-6.EI

Abstract

An unprecedented community outbreak of severe acute respiratory syndrome (SARS) occurred in the Amoy Gardens, a high-rise residential complex in Hong Kong. Droplet, air, contaminated fomites, and rodent pests have been proposed to be mechanisms for transmitting SARS in a short period. We studied nasopharyngeal viral load of SARS patients on admission and their geographic distribution. Higher nasopharyngeal viral load was found in patients living in adjacent units of the same block inhabited by the index patient, while a lower but detectable nasopharyngeal viral load was found in patients living further away from the index patient. This pattern of nasopharyngeal viral load suggested that airborne transmission played an important part in this outbreak in Hong Kong. Contaminated fomites and rodent pests may have also played a role.

Authors+Show Affiliations

United Christian Hospital, Hong Kong Special Administrative Region, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16485474

Citation

Chu, Chung-Ming, et al. "Viral Load Distribution in SARS Outbreak." Emerging Infectious Diseases, vol. 11, no. 12, 2005, pp. 1882-6.
Chu CM, Cheng VC, Hung IF, et al. Viral load distribution in SARS outbreak. Emerging Infect Dis. 2005;11(12):1882-6.
Chu, C. M., Cheng, V. C., Hung, I. F., Chan, K. S., Tang, B. S., Tsang, T. H., Chan, K. H., & Yuen, K. Y. (2005). Viral load distribution in SARS outbreak. Emerging Infectious Diseases, 11(12), 1882-6.
Chu CM, et al. Viral Load Distribution in SARS Outbreak. Emerging Infect Dis. 2005;11(12):1882-6. PubMed PMID: 16485474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Viral load distribution in SARS outbreak. AU - Chu,Chung-Ming, AU - Cheng,Vincent C C, AU - Hung,Ivan F N, AU - Chan,Kin-Sang, AU - Tang,Bone S F, AU - Tsang,Thomas H F, AU - Chan,Kwok-Hung, AU - Yuen,Kwok-Yung, PY - 2006/2/21/pubmed PY - 2006/3/17/medline PY - 2006/2/21/entrez SP - 1882 EP - 6 JF - Emerging infectious diseases JO - Emerging Infect. Dis. VL - 11 IS - 12 N2 - An unprecedented community outbreak of severe acute respiratory syndrome (SARS) occurred in the Amoy Gardens, a high-rise residential complex in Hong Kong. Droplet, air, contaminated fomites, and rodent pests have been proposed to be mechanisms for transmitting SARS in a short period. We studied nasopharyngeal viral load of SARS patients on admission and their geographic distribution. Higher nasopharyngeal viral load was found in patients living in adjacent units of the same block inhabited by the index patient, while a lower but detectable nasopharyngeal viral load was found in patients living further away from the index patient. This pattern of nasopharyngeal viral load suggested that airborne transmission played an important part in this outbreak in Hong Kong. Contaminated fomites and rodent pests may have also played a role. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/16485474/full_citation L2 - https://wwwnc.cdc.gov/eid/article/11/12/04-0949_article.htm DB - PRIME DP - Unbound Medicine ER -