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[Ciguatera: from the etiology of the phenomenon to the treatment of its symptoms].
J Soc Biol. 2005; 199(2):127-39.JS

Abstract

Ciguatera is the most common food poisoning found in the tropical and subtropical areas, acquired by the consumption of marine products. A lot of work concerning its etiology, its epidemiology and its clinical effects, as well as the discovery of the toxins involved, the description of their transfer, the study of their structure and the analysis of their pharmacological effects, have allowed a better understanding of the ciguateric phenomenon. Ciguatera is known to be due to benthic dinoflagellates belonging to the Gambierdiscus gender, in particular G. toxicus. Under specific conditions, this microalga produces gambier-toxins, toxins which are the precursors of other toxins, the ciguatoxins. However, the factors supporting this production are still poorly known, and the implication of others dinoflagellates, cyanophytes or bacteria have been suspected. In contrast, the fish species responsible for the transmission of ciguatera are globally well identified. The clinical symptoms of the intoxication are now well described. They mainly include digestive, neurological and cardiovascular disorders whose preponderance varies according to the nature of the toxins involved, since toxin structures are different between one ocean and the other. The ciguateric intoxication tends to be exported towards non endemic areas where it is still misdiagnosed. No specific antidote exists to date, and it is only by symptomatic or palliative treatments that ciguatera is currently treated.

Authors+Show Affiliations

Laboratoire de Pharmacochimie des Substances Naturelles et Pharmacophores Redox, UMR 152, IRD-Université Paul Sabatier, Centre IRD de Nouméa, BP A5, 98848 Nouméa, Nouvelle Calédonie.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

16485600

Citation

Boydron-Le Garrec, Raphaële, et al. "[Ciguatera: From the Etiology of the Phenomenon to the Treatment of Its Symptoms]." Journal De La Societe De Biologie, vol. 199, no. 2, 2005, pp. 127-39.
Boydron-Le Garrec R, Benoit E, Sauviat MP, et al. [Ciguatera: from the etiology of the phenomenon to the treatment of its symptoms]. J Soc Biol. 2005;199(2):127-39.
Boydron-Le Garrec, R., Benoit, E., Sauviat, M. P., Frostin, M., & Laurent, D. (2005). [Ciguatera: from the etiology of the phenomenon to the treatment of its symptoms]. Journal De La Societe De Biologie, 199(2), 127-39.
Boydron-Le Garrec R, et al. [Ciguatera: From the Etiology of the Phenomenon to the Treatment of Its Symptoms]. J Soc Biol. 2005;199(2):127-39. PubMed PMID: 16485600.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Ciguatera: from the etiology of the phenomenon to the treatment of its symptoms]. AU - Boydron-Le Garrec,Raphaële, AU - Benoit,Evelyne, AU - Sauviat,Martin-Pierre, AU - Frostin,Maryvonne, AU - Laurent,Dominique, PY - 2006/2/21/pubmed PY - 2006/4/6/medline PY - 2006/2/21/entrez SP - 127 EP - 39 JF - Journal de la Societe de biologie JO - J Soc Biol VL - 199 IS - 2 N2 - Ciguatera is the most common food poisoning found in the tropical and subtropical areas, acquired by the consumption of marine products. A lot of work concerning its etiology, its epidemiology and its clinical effects, as well as the discovery of the toxins involved, the description of their transfer, the study of their structure and the analysis of their pharmacological effects, have allowed a better understanding of the ciguateric phenomenon. Ciguatera is known to be due to benthic dinoflagellates belonging to the Gambierdiscus gender, in particular G. toxicus. Under specific conditions, this microalga produces gambier-toxins, toxins which are the precursors of other toxins, the ciguatoxins. However, the factors supporting this production are still poorly known, and the implication of others dinoflagellates, cyanophytes or bacteria have been suspected. In contrast, the fish species responsible for the transmission of ciguatera are globally well identified. The clinical symptoms of the intoxication are now well described. They mainly include digestive, neurological and cardiovascular disorders whose preponderance varies according to the nature of the toxins involved, since toxin structures are different between one ocean and the other. The ciguateric intoxication tends to be exported towards non endemic areas where it is still misdiagnosed. No specific antidote exists to date, and it is only by symptomatic or palliative treatments that ciguatera is currently treated. SN - 1295-0661 UR - https://www.unboundmedicine.com/medline/citation/16485600/[Ciguatera:_from_the_etiology_of_the_phenomenon_to_the_treatment_of_its_symptoms]_ DB - PRIME DP - Unbound Medicine ER -