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Are appR and katF the same Escherichia coli gene encoding a new sigma transcription initiation factor?
Res Microbiol. 1991 Jan; 142(1):29-36.RM

Abstract

The phenotype of Escherichia coli appR pleiotropic mutants has been compared with that of mutants in the katF gene, which lies in the same region and controls expression of catalase HPII (katE) and exonuclease III (xth). All the described characters of appR mutants--reduced pH 2.5 acid phosphatase level, overexpression of alkaline phosphatase and ability of crp or cya mutants to utilize some CAP + cAMP-dependent carbon sources--were reproduced by a katF:: Tn10 insertion. In all cases, the wild-type phenotype was restored by the presence of a plasmid-borne katF+ gene. Conversely, spontaneous appR mutants were hypersensitive to H2O2 to the same degree as katF mutants. We conclude that the appR gene is identical to katF, which encodes a putative new sigma factor (Mulvey and Loewen, 1989).

Authors+Show Affiliations

Service de Biochimie des Protéines, CEN Saclay, Gif-sur-Yvette, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1648776

Citation

Touati, E, et al. "Are appR and katF the Same Escherichia Coli Gene Encoding a New Sigma Transcription Initiation Factor?" Research in Microbiology, vol. 142, no. 1, 1991, pp. 29-36.
Touati E, Dassa E, Dassa J, et al. Are appR and katF the same Escherichia coli gene encoding a new sigma transcription initiation factor? Res Microbiol. 1991;142(1):29-36.
Touati, E., Dassa, E., Dassa, J., Boquet, P. L., & Touati, D. (1991). Are appR and katF the same Escherichia coli gene encoding a new sigma transcription initiation factor? Research in Microbiology, 142(1), 29-36.
Touati E, et al. Are appR and katF the Same Escherichia Coli Gene Encoding a New Sigma Transcription Initiation Factor. Res Microbiol. 1991;142(1):29-36. PubMed PMID: 1648776.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Are appR and katF the same Escherichia coli gene encoding a new sigma transcription initiation factor? AU - Touati,E, AU - Dassa,E, AU - Dassa,J, AU - Boquet,P L, AU - Touati,D, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 29 EP - 36 JF - Research in microbiology JO - Res Microbiol VL - 142 IS - 1 N2 - The phenotype of Escherichia coli appR pleiotropic mutants has been compared with that of mutants in the katF gene, which lies in the same region and controls expression of catalase HPII (katE) and exonuclease III (xth). All the described characters of appR mutants--reduced pH 2.5 acid phosphatase level, overexpression of alkaline phosphatase and ability of crp or cya mutants to utilize some CAP + cAMP-dependent carbon sources--were reproduced by a katF:: Tn10 insertion. In all cases, the wild-type phenotype was restored by the presence of a plasmid-borne katF+ gene. Conversely, spontaneous appR mutants were hypersensitive to H2O2 to the same degree as katF mutants. We conclude that the appR gene is identical to katF, which encodes a putative new sigma factor (Mulvey and Loewen, 1989). SN - 0923-2508 UR - https://www.unboundmedicine.com/medline/citation/1648776/Are_appR_and_katF_the_same_Escherichia_coli_gene_encoding_a_new_sigma_transcription_initiation_factor L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:1648776 DB - PRIME DP - Unbound Medicine ER -