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Effect of optic material and haptic design on anterior capsule opacification and capsulorrhexis contraction.
Am J Ophthalmol. 2006 Mar; 141(3):488-493.AJ

Abstract

PURPOSE

To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction.

DESIGN

Randomized, controlled, double-blind clinical trial with intraindividual comparison.

METHODS

This study was performed at the Department of Ophthalmology, Medical University of Vienna, Austria, and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n = 53 patients), a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n = 52 patients), the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation, standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation, digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score, 0% to 100%), and the capsulorrhexis area (square millimeters) was determined objectively.

RESULTS

One year after surgery, the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P = .4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P = .87) in group 2. Concerning the amount of capsulorrhexis contraction, there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction, P > .05).

CONCLUSION

In the hydrophobic sharp optic edge IOLs that were examined, neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction.

Authors+Show Affiliations

Department of Ophthalmology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16490494

Citation

Sacu, Stefan, et al. "Effect of Optic Material and Haptic Design On Anterior Capsule Opacification and Capsulorrhexis Contraction." American Journal of Ophthalmology, vol. 141, no. 3, 2006, pp. 488-493.
Sacu S, Menapace R, Findl O. Effect of optic material and haptic design on anterior capsule opacification and capsulorrhexis contraction. Am J Ophthalmol. 2006;141(3):488-493.
Sacu, S., Menapace, R., & Findl, O. (2006). Effect of optic material and haptic design on anterior capsule opacification and capsulorrhexis contraction. American Journal of Ophthalmology, 141(3), 488-493.
Sacu S, Menapace R, Findl O. Effect of Optic Material and Haptic Design On Anterior Capsule Opacification and Capsulorrhexis Contraction. Am J Ophthalmol. 2006;141(3):488-493. PubMed PMID: 16490494.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of optic material and haptic design on anterior capsule opacification and capsulorrhexis contraction. AU - Sacu,Stefan, AU - Menapace,Rupert, AU - Findl,Oliver, PY - 2005/08/06/received PY - 2005/10/16/revised PY - 2005/10/19/accepted PY - 2006/2/24/pubmed PY - 2006/3/28/medline PY - 2006/2/24/entrez SP - 488 EP - 493 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 141 IS - 3 N2 - PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized, controlled, double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology, Medical University of Vienna, Austria, and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n = 53 patients), a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n = 52 patients), the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation, standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation, digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score, 0% to 100%), and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery, the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P = .4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P = .87) in group 2. Concerning the amount of capsulorrhexis contraction, there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction, P > .05). CONCLUSION: In the hydrophobic sharp optic edge IOLs that were examined, neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/16490494/Effect_of_optic_material_and_haptic_design_on_anterior_capsule_opacification_and_capsulorrhexis_contraction_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(05)01129-3 DB - PRIME DP - Unbound Medicine ER -