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Scrub typhus, Republic of Palau.
Emerg Infect Dis. 2006 Feb; 12(2):290-5.EI

Abstract

Scrub typhus, caused by Orientia tsutsugamushi, is a severe febrile illness transmitted to humans by trombiculid mites, which normally feed on rodents. The first known outbreak of scrub typhus in Palau occurred in 2001 to 2003 among residents of the remote southwest islands. To determine the extent of scrub typhus distribution in Palau, we tested serum samples from humans and rodents for antibodies to O. tsutsugamushi. Of 212 Palau residents surveyed in 2003, 101 (47.6%) had immunoglobulin G (IgG) antibody titers >1:64, and 56 (26.4%) had concurrent IgG and IgM antibody titers >1:512 and 1:64, respectively. Of 635 banked serum samples collected from Palau residents in 1995, 34 (5.4%) had IgG antibody titers >1:64. Sera collected from rodents (Rattus norvegicus and R. rattus) in 2003 and 2005 were tested, and 18 (28.6%) of 63 had IgG antibody titers >1:64. These findings suggest that scrub typhus is endemic in Palau.

Authors+Show Affiliations

Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. ldemma@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16494757

Citation

Demma, Linda J., et al. "Scrub Typhus, Republic of Palau." Emerging Infectious Diseases, vol. 12, no. 2, 2006, pp. 290-5.
Demma LJ, McQuiston JH, Nicholson WL, et al. Scrub typhus, Republic of Palau. Emerg Infect Dis. 2006;12(2):290-5.
Demma, L. J., McQuiston, J. H., Nicholson, W. L., Murphy, S. M., Marumoto, P., Sengebau-Kingzio, M., Kuartei, S., Durand, A. M., & Swerdlow, D. L. (2006). Scrub typhus, Republic of Palau. Emerging Infectious Diseases, 12(2), 290-5.
Demma LJ, et al. Scrub Typhus, Republic of Palau. Emerg Infect Dis. 2006;12(2):290-5. PubMed PMID: 16494757.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Scrub typhus, Republic of Palau. AU - Demma,Linda J, AU - McQuiston,Jennifer H, AU - Nicholson,William L, AU - Murphy,Staci M, AU - Marumoto,Pearl, AU - Sengebau-Kingzio,Maireng, AU - Kuartei,Stevenson, AU - Durand,A Mark, AU - Swerdlow,David L, PY - 2006/2/24/pubmed PY - 2006/4/6/medline PY - 2006/2/24/entrez SP - 290 EP - 5 JF - Emerging infectious diseases JO - Emerg Infect Dis VL - 12 IS - 2 N2 - Scrub typhus, caused by Orientia tsutsugamushi, is a severe febrile illness transmitted to humans by trombiculid mites, which normally feed on rodents. The first known outbreak of scrub typhus in Palau occurred in 2001 to 2003 among residents of the remote southwest islands. To determine the extent of scrub typhus distribution in Palau, we tested serum samples from humans and rodents for antibodies to O. tsutsugamushi. Of 212 Palau residents surveyed in 2003, 101 (47.6%) had immunoglobulin G (IgG) antibody titers >1:64, and 56 (26.4%) had concurrent IgG and IgM antibody titers >1:512 and 1:64, respectively. Of 635 banked serum samples collected from Palau residents in 1995, 34 (5.4%) had IgG antibody titers >1:64. Sera collected from rodents (Rattus norvegicus and R. rattus) in 2003 and 2005 were tested, and 18 (28.6%) of 63 had IgG antibody titers >1:64. These findings suggest that scrub typhus is endemic in Palau. SN - 1080-6040 UR - https://www.unboundmedicine.com/medline/citation/16494757/Scrub_typhus_Republic_of_Palau_ DB - PRIME DP - Unbound Medicine ER -