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Selective ABTS radical-scavenging activity of prenylated flavonoids from Cudrania tricuspidata.
Biosci Biotechnol Biochem. 2006 Feb; 70(2):427-32.BB

Abstract

The antioxidative properties of five prenylated flavonoids, including new flavanone (2), from the root bark of Cudrania tricuspidata were examined against the ABTS, DPPH, and hydroxyl radicals. In most of the assays to determine their antioxidative properties, the ABTS activity was strongly correlated with DPPH because both methods are responsible for the same chemical property of hydrogen- or electron-donation to the antioxidant. On the other hand, the prenylated flavonoids (1-5) acted differently with both methods; namely, all the prenylated flavonoids strongly scavenged the ABTS radical (IC(50) < 10 microM), while they were inactive against the DPPH radical (IC(50) > 300 microM). Even though isolated 5,7,2',4',-tetrahydroxy-6,5'-diprenylflavanone (3) showed weak reducing power (746 mV) by cyclic voltammetry when compared to quercetin (394 mV), both had similar ABTS activity (IC(50) < 5 microM).

Authors+Show Affiliations

Division of Applied Life Science (BK21 program), Department of Agricultural Chemistry, Institute of Agriculture & Life Sciences, Gyeongsang National University, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16495659

Citation

Lee, Byong Won, et al. "Selective ABTS Radical-scavenging Activity of Prenylated Flavonoids From Cudrania Tricuspidata." Bioscience, Biotechnology, and Biochemistry, vol. 70, no. 2, 2006, pp. 427-32.
Lee BW, Lee JH, Gal SW, et al. Selective ABTS radical-scavenging activity of prenylated flavonoids from Cudrania tricuspidata. Biosci Biotechnol Biochem. 2006;70(2):427-32.
Lee, B. W., Lee, J. H., Gal, S. W., Moon, Y. H., & Park, K. H. (2006). Selective ABTS radical-scavenging activity of prenylated flavonoids from Cudrania tricuspidata. Bioscience, Biotechnology, and Biochemistry, 70(2), 427-32.
Lee BW, et al. Selective ABTS Radical-scavenging Activity of Prenylated Flavonoids From Cudrania Tricuspidata. Biosci Biotechnol Biochem. 2006;70(2):427-32. PubMed PMID: 16495659.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selective ABTS radical-scavenging activity of prenylated flavonoids from Cudrania tricuspidata. AU - Lee,Byong Won, AU - Lee,Jin Hwan, AU - Gal,Sang Wan, AU - Moon,Yea Hwang, AU - Park,Ki Hun, PY - 2006/2/24/pubmed PY - 2006/7/21/medline PY - 2006/2/24/entrez SP - 427 EP - 32 JF - Bioscience, biotechnology, and biochemistry JO - Biosci Biotechnol Biochem VL - 70 IS - 2 N2 - The antioxidative properties of five prenylated flavonoids, including new flavanone (2), from the root bark of Cudrania tricuspidata were examined against the ABTS, DPPH, and hydroxyl radicals. In most of the assays to determine their antioxidative properties, the ABTS activity was strongly correlated with DPPH because both methods are responsible for the same chemical property of hydrogen- or electron-donation to the antioxidant. On the other hand, the prenylated flavonoids (1-5) acted differently with both methods; namely, all the prenylated flavonoids strongly scavenged the ABTS radical (IC(50) < 10 microM), while they were inactive against the DPPH radical (IC(50) > 300 microM). Even though isolated 5,7,2',4',-tetrahydroxy-6,5'-diprenylflavanone (3) showed weak reducing power (746 mV) by cyclic voltammetry when compared to quercetin (394 mV), both had similar ABTS activity (IC(50) < 5 microM). SN - 0916-8451 UR - https://www.unboundmedicine.com/medline/citation/16495659/Selective_ABTS_radical_scavenging_activity_of_prenylated_flavonoids_from_Cudrania_tricuspidata_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/bbb/70.427?lang=en&amp;from=PubMed DB - PRIME DP - Unbound Medicine ER -