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Estrogen receptor gene polymorphisms are associated with recurrence of endometriosis.
Fertil Steril. 2006 Mar; 85(3):764-6.FS

Abstract

The presence of gene polymorphisms of the estrogen receptors ERalpha (PvuII and XbaI) and ERbeta (AluI) in 61 women with endometriosis was investigated. A statistically significant correlation between PvuII ERalpha gene polymorphism (PvuII), both in homozygosity (PP) and in heterozygosity (Pp), and a recurrence of endometriosis was found. In conclusion, women affected by endometriosis with the ERalpha polymorphic allele, even if heterozygous, have a worse prognosis, and these results suggest that the ERalpha gene polymorphisms may be included among the genetic risk factors for endometriosis.

Authors+Show Affiliations

Department of Pediatrics, Gynecology and Reproductive Medicine, University of Siena, Siena, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16500359

Citation

Luisi, Stefano, et al. "Estrogen Receptor Gene Polymorphisms Are Associated With Recurrence of Endometriosis." Fertility and Sterility, vol. 85, no. 3, 2006, pp. 764-6.
Luisi S, Galleri L, Marini F, et al. Estrogen receptor gene polymorphisms are associated with recurrence of endometriosis. Fertil Steril. 2006;85(3):764-6.
Luisi, S., Galleri, L., Marini, F., Ambrosini, G., Brandi, M. L., & Petraglia, F. (2006). Estrogen receptor gene polymorphisms are associated with recurrence of endometriosis. Fertility and Sterility, 85(3), 764-6.
Luisi S, et al. Estrogen Receptor Gene Polymorphisms Are Associated With Recurrence of Endometriosis. Fertil Steril. 2006;85(3):764-6. PubMed PMID: 16500359.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Estrogen receptor gene polymorphisms are associated with recurrence of endometriosis. AU - Luisi,Stefano, AU - Galleri,Letizia, AU - Marini,Francesca, AU - Ambrosini,Guido, AU - Brandi,Maria Luisa, AU - Petraglia,Felice, PY - 2004/12/07/received PY - 2005/08/25/revised PY - 2005/08/25/accepted PY - 2006/2/28/pubmed PY - 2006/3/22/medline PY - 2006/2/28/entrez SP - 764 EP - 6 JF - Fertility and sterility JO - Fertil Steril VL - 85 IS - 3 N2 - The presence of gene polymorphisms of the estrogen receptors ERalpha (PvuII and XbaI) and ERbeta (AluI) in 61 women with endometriosis was investigated. A statistically significant correlation between PvuII ERalpha gene polymorphism (PvuII), both in homozygosity (PP) and in heterozygosity (Pp), and a recurrence of endometriosis was found. In conclusion, women affected by endometriosis with the ERalpha polymorphic allele, even if heterozygous, have a worse prognosis, and these results suggest that the ERalpha gene polymorphisms may be included among the genetic risk factors for endometriosis. SN - 1556-5653 UR - https://www.unboundmedicine.com/medline/citation/16500359/Estrogen_receptor_gene_polymorphisms_are_associated_with_recurrence_of_endometriosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(05)03967-1 DB - PRIME DP - Unbound Medicine ER -