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Uric acid status and its correlates in Hangzhou urban population.
Asia Pac J Clin Nutr. 2006; 15(1):102-6.AP

Abstract

The aim of this study was to investigate the uric acid status and its correlates in relation to selected cardiovascular risk factors in a cross-sectional study in Hangzhou, China. In this cross-sectional study, 186 male (56 +/- 14 yrs) and 85 female (55 +/- 11 yrs) free-living subjects were recruited from the Hangzhou metropolitan area, China. Their physiological parameters were measured. Each subject gave fasting blood, urine and faeces samples, from which serum uric acid and other parameters of biochemistry and haematology were measured by standard methods. Serum uric concentration was 329 +/- 69 micromol/L for male and 237 +/- 53 micromol/L for female (P < 0.0001). Compared with female subjects, males had significantly higher BMI (P = 0.0215), serum triacylglycerol (TAG) (P = 0.0012) and creatinine (P<0.0001), and significantly lower total cholesterol (TC) (P = 0.0013) and HDL-C (P < 0.0001). In the partial correlation analysis, after controlling for sex, age and BMI, serum uric acid was significantly positively correlated with serum concentrations of TC (r = 0.205, P = 0.001), LDL-C (r = 0.229, P < 0.001),TAG (r = 0.172, P = 0.008) and creatinine (r = 0.330, P < 0.001). The results from the present study indicated that prevalence rates of hyperuricaemia are lower in Hangzhou than in Beijing; increased serum uric acid concentration was associated with a cluster of cardiovascular risk factors for the Hangzhou urban population.

Authors+Show Affiliations

Department of Food Science and Nutrition, Zhejiang University, Hangzhou, China. popkin@unc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16500885

Citation

Li, Duo, et al. "Uric Acid Status and Its Correlates in Hangzhou Urban Population." Asia Pacific Journal of Clinical Nutrition, vol. 15, no. 1, 2006, pp. 102-6.
Li D, Yu X, Zhou X, et al. Uric acid status and its correlates in Hangzhou urban population. Asia Pac J Clin Nutr. 2006;15(1):102-6.
Li, D., Yu, X., Zhou, X., Siriamornpun, S., & Wahlqvist, M. L. (2006). Uric acid status and its correlates in Hangzhou urban population. Asia Pacific Journal of Clinical Nutrition, 15(1), 102-6.
Li D, et al. Uric Acid Status and Its Correlates in Hangzhou Urban Population. Asia Pac J Clin Nutr. 2006;15(1):102-6. PubMed PMID: 16500885.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Uric acid status and its correlates in Hangzhou urban population. AU - Li,Duo, AU - Yu,Xiaomei, AU - Zhou,Xiaoqun, AU - Siriamornpun,Sirithon, AU - Wahlqvist,Mark L, PY - 2006/2/28/pubmed PY - 2006/6/17/medline PY - 2006/2/28/entrez SP - 102 EP - 6 JF - Asia Pacific journal of clinical nutrition JO - Asia Pac J Clin Nutr VL - 15 IS - 1 N2 - The aim of this study was to investigate the uric acid status and its correlates in relation to selected cardiovascular risk factors in a cross-sectional study in Hangzhou, China. In this cross-sectional study, 186 male (56 +/- 14 yrs) and 85 female (55 +/- 11 yrs) free-living subjects were recruited from the Hangzhou metropolitan area, China. Their physiological parameters were measured. Each subject gave fasting blood, urine and faeces samples, from which serum uric acid and other parameters of biochemistry and haematology were measured by standard methods. Serum uric concentration was 329 +/- 69 micromol/L for male and 237 +/- 53 micromol/L for female (P < 0.0001). Compared with female subjects, males had significantly higher BMI (P = 0.0215), serum triacylglycerol (TAG) (P = 0.0012) and creatinine (P<0.0001), and significantly lower total cholesterol (TC) (P = 0.0013) and HDL-C (P < 0.0001). In the partial correlation analysis, after controlling for sex, age and BMI, serum uric acid was significantly positively correlated with serum concentrations of TC (r = 0.205, P = 0.001), LDL-C (r = 0.229, P < 0.001),TAG (r = 0.172, P = 0.008) and creatinine (r = 0.330, P < 0.001). The results from the present study indicated that prevalence rates of hyperuricaemia are lower in Hangzhou than in Beijing; increased serum uric acid concentration was associated with a cluster of cardiovascular risk factors for the Hangzhou urban population. SN - 0964-7058 UR - https://www.unboundmedicine.com/medline/citation/16500885/Uric_acid_status_and_its_correlates_in_Hangzhou_urban_population_ L2 - http://apjcn.nhri.org.tw/server/APJCN/15/1/102.pdf DB - PRIME DP - Unbound Medicine ER -