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Serum ferritin in children with attention-deficit hyperactivity disorder.
Pediatr Neurol 2006; 34(3):200-3PN

Abstract

To further define a role for iron deficiency in attention-deficit hyperactivity disorder, serum ferritin was included in a battery of laboratory tests obtained in children attending a clinic for attention deficit disorders. In a total of 68 consecutive patients (ages 5-16 years; 54 male, 14 female), the range of serum ferritin levels was a low of 7.7 ng/mL and a high of 150 ng/mL. The mean (+/-S.D.) serum ferritin level in patients with attention-deficit hyperactivity disorder (39.9 +/- 40.6 ng/mL) was not different from that of control subjects. Seventy-four percent of patients had serum ferritin levels below 50 ng/mL; 44% were below 30 ng/mL; and 18% below 20 ng/mL. None had evidence of iron deficiency anemia. A comparison of the clinical characteristics of the 12 patients with the lowest serum ferritin levels (<20 ng/mL) and 12 with the highest levels (>60 ng/mL) disclosed no significant difference in severity or frequency of attention-deficit hyperactivity disorder and comorbid symptoms or response to medications. In this patient cohort, a causative role for low serum ferritin in attention-deficit hyperactivity disorder has not been confirmed.

Authors+Show Affiliations

Division of Neurology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA. gmillichap@childrensmemorial.orgNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16504789

Citation

Millichap, J Gordon, et al. "Serum Ferritin in Children With Attention-deficit Hyperactivity Disorder." Pediatric Neurology, vol. 34, no. 3, 2006, pp. 200-3.
Millichap JG, Yee MM, Davidson SI. Serum ferritin in children with attention-deficit hyperactivity disorder. Pediatr Neurol. 2006;34(3):200-3.
Millichap, J. G., Yee, M. M., & Davidson, S. I. (2006). Serum ferritin in children with attention-deficit hyperactivity disorder. Pediatric Neurology, 34(3), pp. 200-3.
Millichap JG, Yee MM, Davidson SI. Serum Ferritin in Children With Attention-deficit Hyperactivity Disorder. Pediatr Neurol. 2006;34(3):200-3. PubMed PMID: 16504789.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum ferritin in children with attention-deficit hyperactivity disorder. AU - Millichap,J Gordon, AU - Yee,Michelle M, AU - Davidson,Sonia I, PY - 2005/05/18/received PY - 2005/08/23/revised PY - 2005/09/09/accepted PY - 2006/3/1/pubmed PY - 2006/6/23/medline PY - 2006/3/1/entrez SP - 200 EP - 3 JF - Pediatric neurology JO - Pediatr. Neurol. VL - 34 IS - 3 N2 - To further define a role for iron deficiency in attention-deficit hyperactivity disorder, serum ferritin was included in a battery of laboratory tests obtained in children attending a clinic for attention deficit disorders. In a total of 68 consecutive patients (ages 5-16 years; 54 male, 14 female), the range of serum ferritin levels was a low of 7.7 ng/mL and a high of 150 ng/mL. The mean (+/-S.D.) serum ferritin level in patients with attention-deficit hyperactivity disorder (39.9 +/- 40.6 ng/mL) was not different from that of control subjects. Seventy-four percent of patients had serum ferritin levels below 50 ng/mL; 44% were below 30 ng/mL; and 18% below 20 ng/mL. None had evidence of iron deficiency anemia. A comparison of the clinical characteristics of the 12 patients with the lowest serum ferritin levels (<20 ng/mL) and 12 with the highest levels (>60 ng/mL) disclosed no significant difference in severity or frequency of attention-deficit hyperactivity disorder and comorbid symptoms or response to medications. In this patient cohort, a causative role for low serum ferritin in attention-deficit hyperactivity disorder has not been confirmed. SN - 0887-8994 UR - https://www.unboundmedicine.com/medline/citation/16504789/Serum_ferritin_in_children_with_attention_deficit_hyperactivity_disorder_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0887-8994(05)00547-3 DB - PRIME DP - Unbound Medicine ER -