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Resveratrol in cardioprotection: a therapeutic promise of alternative medicine.
Mol Interv 2006; 6(1):36-47MI

Abstract

Resveratrol, a polyphenol phytoalexin, possesses diverse biochemical and physiological actions, including estrogenic, antiplatelet, and anti-inflammatory properties. Several recent studies determined the cardioprotective abilities of resveratrol. Both in experiments (acute) and in chronic models, resveratrol attenuates myocardial ischemic reperfusion injury, atherosclerosis, and reduces ventricular arrhythmias. It appears that resveratrol-mediated cardioprotection is achieved through the preconditioning effect (the best yet devised method of cardioprotection), rather than direct protection. Thus, resveratrol likely fulfills the definition of a pharmacological preconditioning compound and gives hope to the therapeutic promise of alternative medicine.

Authors+Show Affiliations

Cardiovascular Research Center, University of Connecticut School of Medicine, Farmington, CT 06030-1110, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

16507749

Citation

Das, Dipak K., and Nilanjana Maulik. "Resveratrol in Cardioprotection: a Therapeutic Promise of Alternative Medicine." Molecular Interventions, vol. 6, no. 1, 2006, pp. 36-47.
Das DK, Maulik N. Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. Mol Interv. 2006;6(1):36-47.
Das, D. K., & Maulik, N. (2006). Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. Molecular Interventions, 6(1), pp. 36-47.
Das DK, Maulik N. Resveratrol in Cardioprotection: a Therapeutic Promise of Alternative Medicine. Mol Interv. 2006;6(1):36-47. PubMed PMID: 16507749.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. AU - Das,Dipak K, AU - Maulik,Nilanjana, PY - 2006/3/2/pubmed PY - 2007/6/15/medline PY - 2006/3/2/entrez SP - 36 EP - 47 JF - Molecular interventions JO - Mol. Interv. VL - 6 IS - 1 N2 - Resveratrol, a polyphenol phytoalexin, possesses diverse biochemical and physiological actions, including estrogenic, antiplatelet, and anti-inflammatory properties. Several recent studies determined the cardioprotective abilities of resveratrol. Both in experiments (acute) and in chronic models, resveratrol attenuates myocardial ischemic reperfusion injury, atherosclerosis, and reduces ventricular arrhythmias. It appears that resveratrol-mediated cardioprotection is achieved through the preconditioning effect (the best yet devised method of cardioprotection), rather than direct protection. Thus, resveratrol likely fulfills the definition of a pharmacological preconditioning compound and gives hope to the therapeutic promise of alternative medicine. SN - 1534-0384 UR - https://www.unboundmedicine.com/medline/citation/16507749/Resveratrol_in_cardioprotection:_a_therapeutic_promise_of_alternative_medicine_ L2 - https://medlineplus.gov/complementaryandintegrativemedicine.html DB - PRIME DP - Unbound Medicine ER -