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The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers.
Clin Infect Dis 2006; 42(7):897-903CI

Abstract

BACKGROUND

Exposure to tobacco smoke is associated with higher risk of Streptococcus pneumoniae and Haemophilus influenzae infection. The aim of this study was to determine the influence of smoking and exposure to tobacco smoke on S. pneumoniae and H. influenzae carriage rates in children and their mothers.

PATIENTS AND METHODS

We performed a cross-sectional surveillance study of nasopharyngeal and oropharyngeal carriage of S. pneumoniae and H. influenzae in 208 children aged <60 months and their mothers. Smoking exposure and medical history were recorded. Carriage rates for children and their mothers in nasopharyngeal and oropharyngeal specimens were analyzed on the basis of smoking exposure.

RESULTS

The S. pneumoniae carriage rate was higher among children exposed to smoking than among nonexposed children (76% vs. 60%; P=.016). Exposed children more frequently carried S. pneumoniae serotypes included in the conjugate 7-valent vaccine, compared with nonexposed children (49% vs. 30% of all S. pneumoniae-positive nasopharyngeal cultures; P=.02). Carriage rates of S. pneumoniae were higher among mothers who smoked than among mothers exposed to smoking and among nonexposed mothers (32%, 15%, and 12%, respectively; P=.03). There were no differences in H. influenzae carriage rates between children and mothers from smoking and nonsmoking families.

CONCLUSIONS

Exposure to tobacco smoke increased S. pneumoniae carriage rates in general and for carriage of serotypes included in the conjugate 7-valent vaccine in particular in children. Smoking mothers had a higher S. pneumoniae carriage rate than did nonsmoking mothers. Smoking or exposure to smoking did not increase H. influenzae carriage rates in children and mothers.

Authors+Show Affiliations

Pediatric Infectious Disease Unit, Soroka University Medical Center, The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. dudi@bgu.ac.ilNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16511750

Citation

Greenberg, David, et al. "The Contribution of Smoking and Exposure to Tobacco Smoke to Streptococcus Pneumoniae and Haemophilus Influenzae Carriage in Children and Their Mothers." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 42, no. 7, 2006, pp. 897-903.
Greenberg D, Givon-Lavi N, Broides A, et al. The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clin Infect Dis. 2006;42(7):897-903.
Greenberg, D., Givon-Lavi, N., Broides, A., Blancovich, I., Peled, N., & Dagan, R. (2006). The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 42(7), pp. 897-903.
Greenberg D, et al. The Contribution of Smoking and Exposure to Tobacco Smoke to Streptococcus Pneumoniae and Haemophilus Influenzae Carriage in Children and Their Mothers. Clin Infect Dis. 2006 Apr 1;42(7):897-903. PubMed PMID: 16511750.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The contribution of smoking and exposure to tobacco smoke to Streptococcus pneumoniae and Haemophilus influenzae carriage in children and their mothers. AU - Greenberg,David, AU - Givon-Lavi,Noga, AU - Broides,Arnon, AU - Blancovich,Irena, AU - Peled,Nechama, AU - Dagan,Ron, Y1 - 2006/02/16/ PY - 2005/07/14/received PY - 2005/11/29/accepted PY - 2006/3/3/pubmed PY - 2006/6/9/medline PY - 2006/3/3/entrez SP - 897 EP - 903 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin. Infect. Dis. VL - 42 IS - 7 N2 - BACKGROUND: Exposure to tobacco smoke is associated with higher risk of Streptococcus pneumoniae and Haemophilus influenzae infection. The aim of this study was to determine the influence of smoking and exposure to tobacco smoke on S. pneumoniae and H. influenzae carriage rates in children and their mothers. PATIENTS AND METHODS: We performed a cross-sectional surveillance study of nasopharyngeal and oropharyngeal carriage of S. pneumoniae and H. influenzae in 208 children aged <60 months and their mothers. Smoking exposure and medical history were recorded. Carriage rates for children and their mothers in nasopharyngeal and oropharyngeal specimens were analyzed on the basis of smoking exposure. RESULTS: The S. pneumoniae carriage rate was higher among children exposed to smoking than among nonexposed children (76% vs. 60%; P=.016). Exposed children more frequently carried S. pneumoniae serotypes included in the conjugate 7-valent vaccine, compared with nonexposed children (49% vs. 30% of all S. pneumoniae-positive nasopharyngeal cultures; P=.02). Carriage rates of S. pneumoniae were higher among mothers who smoked than among mothers exposed to smoking and among nonexposed mothers (32%, 15%, and 12%, respectively; P=.03). There were no differences in H. influenzae carriage rates between children and mothers from smoking and nonsmoking families. CONCLUSIONS: Exposure to tobacco smoke increased S. pneumoniae carriage rates in general and for carriage of serotypes included in the conjugate 7-valent vaccine in particular in children. Smoking mothers had a higher S. pneumoniae carriage rate than did nonsmoking mothers. Smoking or exposure to smoking did not increase H. influenzae carriage rates in children and mothers. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/16511750/The_contribution_of_smoking_and_exposure_to_tobacco_smoke_to_Streptococcus_pneumoniae_and_Haemophilus_influenzae_carriage_in_children_and_their_mothers_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/500935 DB - PRIME DP - Unbound Medicine ER -