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[Clinicodiagnostic significance of gastroesophageal reflux and structural changes in the esophagus and stomach in bronchial asthma].
Klin Med (Mosk). 2006; 84(1):34-7.KM

Abstract

Four hundred patients with bronchial asthma (BA) were questioned. Complex clinical and instrumental examination of 60 patients with BA and endoscopic-positive gastroesophageal reflux disease was carried out; the control groups included 30 patients with BA alone and 30 patients with GERD alone. Clinical symptoms of GERD were revealed in 58% of BA patients; endoscopic-positive GERD was diagnosed in 48.6% of BA patients. The study proved the connection between the degree of respiratory disturbances, on the one hand, and the degree of esophagitis and the level of intraesophageal pH, on the other, in patients with BA plus GERD. The study also established the role of esophageal and gastric epitheliocytes, producing endothelin-1, melatonin, NO-synthase, and calretinin, in the occurrence of mutual exacerbation syndrome.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

16512394

Citation

Kozlova, I V., et al. "[Clinicodiagnostic Significance of Gastroesophageal Reflux and Structural Changes in the Esophagus and Stomach in Bronchial Asthma]." Klinicheskaia Meditsina, vol. 84, no. 1, 2006, pp. 34-7.
Kozlova IV, Kvetnoĭ IM, Slavkina EA, et al. [Clinicodiagnostic significance of gastroesophageal reflux and structural changes in the esophagus and stomach in bronchial asthma]. Klin Med (Mosk). 2006;84(1):34-7.
Kozlova, I. V., Kvetnoĭ, I. M., Slavkina, E. A., & Pakhomova, A. L. (2006). [Clinicodiagnostic significance of gastroesophageal reflux and structural changes in the esophagus and stomach in bronchial asthma]. Klinicheskaia Meditsina, 84(1), 34-7.
Kozlova IV, et al. [Clinicodiagnostic Significance of Gastroesophageal Reflux and Structural Changes in the Esophagus and Stomach in Bronchial Asthma]. Klin Med (Mosk). 2006;84(1):34-7. PubMed PMID: 16512394.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinicodiagnostic significance of gastroesophageal reflux and structural changes in the esophagus and stomach in bronchial asthma]. AU - Kozlova,I V, AU - Kvetnoĭ,I M, AU - Slavkina,E A, AU - Pakhomova,A L, PY - 2006/3/4/pubmed PY - 2006/5/12/medline PY - 2006/3/4/entrez SP - 34 EP - 7 JF - Klinicheskaia meditsina JO - Klin Med (Mosk) VL - 84 IS - 1 N2 - Four hundred patients with bronchial asthma (BA) were questioned. Complex clinical and instrumental examination of 60 patients with BA and endoscopic-positive gastroesophageal reflux disease was carried out; the control groups included 30 patients with BA alone and 30 patients with GERD alone. Clinical symptoms of GERD were revealed in 58% of BA patients; endoscopic-positive GERD was diagnosed in 48.6% of BA patients. The study proved the connection between the degree of respiratory disturbances, on the one hand, and the degree of esophagitis and the level of intraesophageal pH, on the other, in patients with BA plus GERD. The study also established the role of esophageal and gastric epitheliocytes, producing endothelin-1, melatonin, NO-synthase, and calretinin, in the occurrence of mutual exacerbation syndrome. SN - 0023-2149 UR - https://www.unboundmedicine.com/medline/citation/16512394/[Clinicodiagnostic_significance_of_gastroesophageal_reflux_and_structural_changes_in_the_esophagus_and_stomach_in_bronchial_asthma]_ L2 - http://www.diseaseinfosearch.org/result/633 DB - PRIME DP - Unbound Medicine ER -