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Peripheral arterial disease in patients with diabetes.
J Am Coll Cardiol 2006; 47(5):921-9JACC

Abstract

Peripheral arterial disease (PAD) is a chronic, lifestyle-limiting disease and is an independent predictor of cardiovascular and cerebrovascular ischemic events. Despite the recognition that PAD is associated with a marked increase in the risk of ischemic events, this particular manifestation of systemic atherosclerosis is largely underdiagnosed and undertreated. The risk of PAD is markedly increased among individuals with diabetes, and ischemic event rates are higher in diabetic individuals with PAD than in comparable non-diabetic populations. Consequently, early diagnosis and treatment of PAD in patients with diabetes is critically important in order to reduce the risk of cardiovascular events, minimize the risk of long-term disability, and improve quality of life. A diagnosis of PAD in patients with diabetes mandates a multi-faceted treatment approach, involving aggressive risk-factor modification, antiplatelet therapy, and revascularization procedures. The American Diabetes Association recently issued a consensus statement on the epidemiology, pathophysiology, diagnosis, and management of PAD in patients with diabetes. This article will review the clinical implications of the consensus statement and highlight the treatment options available in order to help prevent future ischemic events in diabetic individuals with PAD.

Authors+Show Affiliations

Mid America Heart Institute, University of Missouri-Kansas City, Saint Luke's Hospital, Kansas City, Missouri 64111, USA. smarso@saint-lukes.orgNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16516072

Citation

Marso, Steven P., and William R. Hiatt. "Peripheral Arterial Disease in Patients With Diabetes." Journal of the American College of Cardiology, vol. 47, no. 5, 2006, pp. 921-9.
Marso SP, Hiatt WR. Peripheral arterial disease in patients with diabetes. J Am Coll Cardiol. 2006;47(5):921-9.
Marso, S. P., & Hiatt, W. R. (2006). Peripheral arterial disease in patients with diabetes. Journal of the American College of Cardiology, 47(5), pp. 921-9.
Marso SP, Hiatt WR. Peripheral Arterial Disease in Patients With Diabetes. J Am Coll Cardiol. 2006 Mar 7;47(5):921-9. PubMed PMID: 16516072.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Peripheral arterial disease in patients with diabetes. AU - Marso,Steven P, AU - Hiatt,William R, Y1 - 2006/02/09/ PY - 2005/04/15/received PY - 2005/08/18/revised PY - 2005/09/08/accepted PY - 2006/3/7/pubmed PY - 2006/5/18/medline PY - 2006/3/7/entrez SP - 921 EP - 9 JF - Journal of the American College of Cardiology JO - J. Am. Coll. Cardiol. VL - 47 IS - 5 N2 - Peripheral arterial disease (PAD) is a chronic, lifestyle-limiting disease and is an independent predictor of cardiovascular and cerebrovascular ischemic events. Despite the recognition that PAD is associated with a marked increase in the risk of ischemic events, this particular manifestation of systemic atherosclerosis is largely underdiagnosed and undertreated. The risk of PAD is markedly increased among individuals with diabetes, and ischemic event rates are higher in diabetic individuals with PAD than in comparable non-diabetic populations. Consequently, early diagnosis and treatment of PAD in patients with diabetes is critically important in order to reduce the risk of cardiovascular events, minimize the risk of long-term disability, and improve quality of life. A diagnosis of PAD in patients with diabetes mandates a multi-faceted treatment approach, involving aggressive risk-factor modification, antiplatelet therapy, and revascularization procedures. The American Diabetes Association recently issued a consensus statement on the epidemiology, pathophysiology, diagnosis, and management of PAD in patients with diabetes. This article will review the clinical implications of the consensus statement and highlight the treatment options available in order to help prevent future ischemic events in diabetic individuals with PAD. SN - 1558-3597 UR - https://www.unboundmedicine.com/medline/citation/16516072/Peripheral_arterial_disease_in_patients_with_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0735-1097(05)02862-7 DB - PRIME DP - Unbound Medicine ER -