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Comparison of butorphanol and thiopentone vs fentanyl and thiopentone for laryngeal mask airway insertion.
J Clin Anesth. 2006 Feb; 18(1):8-11.JC

Abstract

STUDY OBJECTIVE

To compare laryngeal mask airway (LMA) insertion conditions using a combination of butorphanol and thiopentone vs fentanyl and thiopentone.

DESIGN

Prospective, randomized, and double-blind study.

SETTING

Operating theater.

PATIENTS

One hundred four females, with American Society of Anesthesiologists grades I and II, diagnosed with carcinoma cervix scheduled for intracavitary implant placement, were recruited into the study. The patients were randomly divided into 2 groups of 52 each.

INTERVENTION

Anesthesia was induced with butorphanol (30 microg kg(-1)) and thiopentone in group B and fentanyl (1.5 microg kg(-1)) and thiopentone in group F, followed by LMA insertion. Anesthesia was maintained with O2, N2O, and isoflurane with spontaneous ventilation.

MEASUREMENTS

Six variables were noted on a 3-point scale: jaw relaxation (nil/slight/gross), ease of insertion (easy/difficult/impossible), swallowing (nil/slight/gross), coughing/gagging (nil/slight/gross), limb/head movement (nil/slight/gross), and laryngospasm (nil/slight/gross). Postoperatively, sedation score was assessed on a 4-point scale at 1/2 hour, 1 hour, and 2 hours.

MAIN RESULTS

The 2 groups were demographically similar. Incidence of full jaw relaxation at first attempt was significantly higher in group B vs F (48 vs 35 patients, P = 0.003). Insertion was easy in 48 vs 37 patients in group B and F, respectively (P = 0.017). The incidence of swallowing, patient movements, and laryngospasm was comparable among the groups. Coughing/gagging was significantly lower in group B (P = 0.008). Significantly more patients were sedated in group B at 1/2 hour (P = 0.010) and 1 hour (P = 0.000). None of the patients were deeply sedated at 1 hour. At 2 hours, all patients were awake.

CONCLUSION

The use of butorphanol and thiopentone as induction agents produced excellent LMA insertion conditions compared to fentanyl and thiopentone (98% vs 86% success rate with 92% vs 71% easy insertion).

Authors+Show Affiliations

Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh-160012, India.No affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16517325

Citation

Chari, Pramila, and Babita Ghai. "Comparison of Butorphanol and Thiopentone Vs Fentanyl and Thiopentone for Laryngeal Mask Airway Insertion." Journal of Clinical Anesthesia, vol. 18, no. 1, 2006, pp. 8-11.
Chari P, Ghai B. Comparison of butorphanol and thiopentone vs fentanyl and thiopentone for laryngeal mask airway insertion. J Clin Anesth. 2006;18(1):8-11.
Chari, P., & Ghai, B. (2006). Comparison of butorphanol and thiopentone vs fentanyl and thiopentone for laryngeal mask airway insertion. Journal of Clinical Anesthesia, 18(1), 8-11.
Chari P, Ghai B. Comparison of Butorphanol and Thiopentone Vs Fentanyl and Thiopentone for Laryngeal Mask Airway Insertion. J Clin Anesth. 2006;18(1):8-11. PubMed PMID: 16517325.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of butorphanol and thiopentone vs fentanyl and thiopentone for laryngeal mask airway insertion. AU - Chari,Pramila, AU - Ghai,Babita, PY - 2004/08/19/received PY - 2005/04/28/accepted PY - 2006/3/7/pubmed PY - 2006/9/13/medline PY - 2006/3/7/entrez SP - 8 EP - 11 JF - Journal of clinical anesthesia JO - J Clin Anesth VL - 18 IS - 1 N2 - STUDY OBJECTIVE: To compare laryngeal mask airway (LMA) insertion conditions using a combination of butorphanol and thiopentone vs fentanyl and thiopentone. DESIGN: Prospective, randomized, and double-blind study. SETTING: Operating theater. PATIENTS: One hundred four females, with American Society of Anesthesiologists grades I and II, diagnosed with carcinoma cervix scheduled for intracavitary implant placement, were recruited into the study. The patients were randomly divided into 2 groups of 52 each. INTERVENTION: Anesthesia was induced with butorphanol (30 microg kg(-1)) and thiopentone in group B and fentanyl (1.5 microg kg(-1)) and thiopentone in group F, followed by LMA insertion. Anesthesia was maintained with O2, N2O, and isoflurane with spontaneous ventilation. MEASUREMENTS: Six variables were noted on a 3-point scale: jaw relaxation (nil/slight/gross), ease of insertion (easy/difficult/impossible), swallowing (nil/slight/gross), coughing/gagging (nil/slight/gross), limb/head movement (nil/slight/gross), and laryngospasm (nil/slight/gross). Postoperatively, sedation score was assessed on a 4-point scale at 1/2 hour, 1 hour, and 2 hours. MAIN RESULTS: The 2 groups were demographically similar. Incidence of full jaw relaxation at first attempt was significantly higher in group B vs F (48 vs 35 patients, P = 0.003). Insertion was easy in 48 vs 37 patients in group B and F, respectively (P = 0.017). The incidence of swallowing, patient movements, and laryngospasm was comparable among the groups. Coughing/gagging was significantly lower in group B (P = 0.008). Significantly more patients were sedated in group B at 1/2 hour (P = 0.010) and 1 hour (P = 0.000). None of the patients were deeply sedated at 1 hour. At 2 hours, all patients were awake. CONCLUSION: The use of butorphanol and thiopentone as induction agents produced excellent LMA insertion conditions compared to fentanyl and thiopentone (98% vs 86% success rate with 92% vs 71% easy insertion). SN - 0952-8180 UR - https://www.unboundmedicine.com/medline/citation/16517325/Comparison_of_butorphanol_and_thiopentone_vs_fentanyl_and_thiopentone_for_laryngeal_mask_airway_insertion_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0952-8180(05)00323-5 DB - PRIME DP - Unbound Medicine ER -