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Clinical study of 20 children with scrub typhus at Chiang Rai Regional Hospital.
J Med Assoc Thai 2005; 88(12):1867-72JM

Abstract

20 children, diagnosed with scrub typhus who attended Chiang Rai Regional Hospital during a period of 6 months from June 2003 to December 2003, were studied prospectively. All cases were serologically proved to be scrub typhus by using Dipstick or indirect immunofluorescent antibody (IFA) technique. The most common clinical feature was eschar (75%). Others included hepatomegaly (65%), cough (60%), lymphadenopathy (40%), tachypnea (35%), constipation (25%), abdominal pain (20%), edema (20%), splenomegaly (15%), vomiting (15%), rash (15%) and petichia (5%) respectively. Chest radiography showed abnormalities in 85% with mostly bilateral interstitial infiltrations. Elevated of SGOT: SGPT were detected in 18 (90%) and 15 (75%) cases. Hypoalbuminemia was detected in 12 (60%) cases. Complete blood count showed PMN leukocytosis (> 60%) in 12 (60%) cases, lymphocytosis (> 40%) and atypical lymphocytosis (> 5%) in 1 (5%) case each and thrombocytopenia in 16 (80%) cases. The Weil-Felix test was positive in 1 (5%) case. Complications were pneumonia with or without pulmonary edema, meningitis and shock. Chloramphenicol and doxycycline were successfully treated and roxithromycin was not effective.

Authors+Show Affiliations

Pediatric Unit, Chiang Rai Prachanukraw Hospital, Chiang Rai 57000, Thailand.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16518987

Citation

Chanta, Chulapong, and Suwalee Chanta. "Clinical Study of 20 Children With Scrub Typhus at Chiang Rai Regional Hospital." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 88, no. 12, 2005, pp. 1867-72.
Chanta C, Chanta S. Clinical study of 20 children with scrub typhus at Chiang Rai Regional Hospital. J Med Assoc Thai. 2005;88(12):1867-72.
Chanta, C., & Chanta, S. (2005). Clinical study of 20 children with scrub typhus at Chiang Rai Regional Hospital. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 88(12), pp. 1867-72.
Chanta C, Chanta S. Clinical Study of 20 Children With Scrub Typhus at Chiang Rai Regional Hospital. J Med Assoc Thai. 2005;88(12):1867-72. PubMed PMID: 16518987.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical study of 20 children with scrub typhus at Chiang Rai Regional Hospital. AU - Chanta,Chulapong, AU - Chanta,Suwalee, PY - 2006/3/8/pubmed PY - 2006/4/12/medline PY - 2006/3/8/entrez SP - 1867 EP - 72 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 88 IS - 12 N2 - 20 children, diagnosed with scrub typhus who attended Chiang Rai Regional Hospital during a period of 6 months from June 2003 to December 2003, were studied prospectively. All cases were serologically proved to be scrub typhus by using Dipstick or indirect immunofluorescent antibody (IFA) technique. The most common clinical feature was eschar (75%). Others included hepatomegaly (65%), cough (60%), lymphadenopathy (40%), tachypnea (35%), constipation (25%), abdominal pain (20%), edema (20%), splenomegaly (15%), vomiting (15%), rash (15%) and petichia (5%) respectively. Chest radiography showed abnormalities in 85% with mostly bilateral interstitial infiltrations. Elevated of SGOT: SGPT were detected in 18 (90%) and 15 (75%) cases. Hypoalbuminemia was detected in 12 (60%) cases. Complete blood count showed PMN leukocytosis (> 60%) in 12 (60%) cases, lymphocytosis (> 40%) and atypical lymphocytosis (> 5%) in 1 (5%) case each and thrombocytopenia in 16 (80%) cases. The Weil-Felix test was positive in 1 (5%) case. Complications were pneumonia with or without pulmonary edema, meningitis and shock. Chloramphenicol and doxycycline were successfully treated and roxithromycin was not effective. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/16518987/Clinical_study_of_20_children_with_scrub_typhus_at_Chiang_Rai_Regional_Hospital_ L2 - http://www.diseaseinfosearch.org/result/7277 DB - PRIME DP - Unbound Medicine ER -