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Antioxidant flavonol glycosides from Schinus molle.
Phytother Res. 2006 Mar; 20(3):200-5.PR

Abstract

Chromatographic separation of aqueous MeOH extract of the leaves of Schinus molle L. has yielded two new acylated quercetin glycosides, named isoquercitrin 6''-O-p-hydroxybenzoate (12) and 2''-O-alpha-L-rhamnopyranosyl-hyperin 6''-O-gallate (13), together with 12 known polyphenolic metabolites for the first time from this species, namely gallic acid (1), methyl gallate (2), chlorogenic acid (3), 2''-alpha-L-rhamnopyranosyl-hyperin (4), quercetin 3-O-beta-D-neohesperidoside (5), miquelianin (6), quercetin 3-O-beta-D-galacturonopyranoside (7), isoquercitrin (8), hyperin (9), isoquercitrin 6''-gallate (10), hyperin 6''-O-gallate (11) and (+)-catechin (14). Their structures were established on the basis of chromatographic properties, chemical, spectroscopic (UV, 1H, 13C NMR) and ESI-MS (positive and negative modes) analyses. Compounds 4-9 and 11 exhibited moderate to strong radical scavenging properties on lipid peroxidation, hydroxyl radical and superoxide anion generations with the highest activities shown by 6 and 7 in comparison with that of quercetin as a positive control in vitro.

Authors+Show Affiliations

Chemistry of Tannins and Leather Technology Department, National Research Center, El-Behoose St. 31, Dokki, Cairo, Egypt. msmarzouk@yahoo.co.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16521111

Citation

Marzouk, Mohamed S., et al. "Antioxidant Flavonol Glycosides From Schinus Molle." Phytotherapy Research : PTR, vol. 20, no. 3, 2006, pp. 200-5.
Marzouk MS, Moharram FA, Haggag EG, et al. Antioxidant flavonol glycosides from Schinus molle. Phytother Res. 2006;20(3):200-5.
Marzouk, M. S., Moharram, F. A., Haggag, E. G., Ibrahim, M. T., & Badary, O. A. (2006). Antioxidant flavonol glycosides from Schinus molle. Phytotherapy Research : PTR, 20(3), 200-5.
Marzouk MS, et al. Antioxidant Flavonol Glycosides From Schinus Molle. Phytother Res. 2006;20(3):200-5. PubMed PMID: 16521111.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant flavonol glycosides from Schinus molle. AU - Marzouk,Mohamed S, AU - Moharram,Fatma A, AU - Haggag,Eman G, AU - Ibrahim,Magda T, AU - Badary,Osama A, PY - 2006/3/8/pubmed PY - 2006/6/10/medline PY - 2006/3/8/entrez SP - 200 EP - 5 JF - Phytotherapy research : PTR JO - Phytother Res VL - 20 IS - 3 N2 - Chromatographic separation of aqueous MeOH extract of the leaves of Schinus molle L. has yielded two new acylated quercetin glycosides, named isoquercitrin 6''-O-p-hydroxybenzoate (12) and 2''-O-alpha-L-rhamnopyranosyl-hyperin 6''-O-gallate (13), together with 12 known polyphenolic metabolites for the first time from this species, namely gallic acid (1), methyl gallate (2), chlorogenic acid (3), 2''-alpha-L-rhamnopyranosyl-hyperin (4), quercetin 3-O-beta-D-neohesperidoside (5), miquelianin (6), quercetin 3-O-beta-D-galacturonopyranoside (7), isoquercitrin (8), hyperin (9), isoquercitrin 6''-gallate (10), hyperin 6''-O-gallate (11) and (+)-catechin (14). Their structures were established on the basis of chromatographic properties, chemical, spectroscopic (UV, 1H, 13C NMR) and ESI-MS (positive and negative modes) analyses. Compounds 4-9 and 11 exhibited moderate to strong radical scavenging properties on lipid peroxidation, hydroxyl radical and superoxide anion generations with the highest activities shown by 6 and 7 in comparison with that of quercetin as a positive control in vitro. SN - 0951-418X UR - https://www.unboundmedicine.com/medline/citation/16521111/Antioxidant_flavonol_glycosides_from_Schinus_molle_ L2 - https://doi.org/10.1002/ptr.1834 DB - PRIME DP - Unbound Medicine ER -